Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 18/20 | 0.60 |
| ▸ | RARB | P10826 | 9/20 | 0.60 |
| ▸ | RARA | P10276 | 9/20 | 0.60 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL345649 | 0.98 | RARG (0.58) | RARGRARBRARARXRAPDK2 | |
| SCHEMBL3876602 | 0.90 | RARG (0.75) | RARGRARBRARARXRA | |
| SCHEMBL3877740 | 0.88 | RARG (0.73) | RARGRARBRARARXRA | |
| SCHEMBL956982 | 0.87 | RARG (0.67) | RARGRARBRARARXRA | |
| SCHEMBL345356 | 0.87 | RARG (0.79) | RARGRARBRARARXRA | |
| SCHEMBL957264 | 0.86 | RARG (0.66) | RARGRARBRARARXRA | |
| SCHEMBL5846621 | 0.86 | RARG (0.77) | RARGRARBRARARXRA | |
| SCHEMBL959254 | 0.86 | RARG (0.66) | RARGRARBRARARXRA | |
| SCHEMBL343651 | 0.86 | RARG (0.78) | RARGRARBRARARXRA | |
| SCHEMBL10002006 | 0.86 | RARG (0.71) | RARGRARBRARARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8362082-B2 | Biphenyl compound selective agonists of gamma RAR receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2013-01-29 | — | — | US | disclosed |
| US-20120016031-A1 | BIPHENYL COMPOUND SELECTIVE AGONISTS OF GAMMA RAR RECEPTORS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2012-01-19 | — | — | US | disclosed |
| US-8049034-B2 | Biphenyl compound selective agonists of gamma RAR receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-11-01 | — | — | US | disclosed |
| US-20090023811-A1 | Biphenyl compound selective agonists of gamma RAR receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023811-A1 | Biphenyl compound selective agonists of gamma RAR receptors | RARG, RARB, RARA | RARG 1/4885RARB 2/4885RARA 3/4885 |
| US-20120016031-A1 | BIPHENYL COMPOUND SELECTIVE AGONISTS OF GAMMA RAR RECEPTORS | RARG, RARB, RARA | RARG 1/4885RARB 2/4885RARA 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.