SCHEMBL387694

SCHEMBL387694

CON1C(=O)CCC(=O)[C@]1(C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)Nc1ccc([N+](=O)[O-])cc1)C(C)C

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 2/20 0.40
ELANE P08246 5/20 0.39
FKBP4 Q02790 1/20 0.37
KCNH2 Q12809 1/20 0.35
XIAP P98170 1/20 0.34
MLX Q9UH92 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
LMNA P02545 1/20 0.34
TRPV1 Q8NER1 1/20 0.34
CMA1 P23946 1/20 0.34
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
MMP2 P08253 1/20 0.33
MMP9 P14780 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7235515 0.91 TACR1 (0.41) TACR1ELANEFKBP4XIAPMLX
SCHEMBL398010 0.91 KCNH2 (0.39) TACR1FKBP4KCNH2MEN1KMT2A
SCHEMBL846697 0.87 FKBP4 (0.51) TACR1FKBP4CMA1
SCHEMBL2682605 0.87 TACR1 (0.40) TACR1FKBP4KCNH2TRPV1CMA1
SCHEMBL1451494 0.85 MEN1 (0.40) MEN1KMT2ALMNAMMP9
SCHEMBL3244930 0.84 ELANE (0.43) TACR1ELANEFKBP4KCNH2XIAP
SCHEMBL3926322 0.83 TACR1 (0.41) TACR1ELANEFKBP4XIAPMLX
SCHEMBL2289363 0.83 ELANE (0.42) ELANEXIAPMLXCMA1
SCHEMBL5134830 0.83 KDM4E (0.40) ELANECYP3A4CYP2C9CYP2C19
SCHEMBL8662040 0.82 ELANE (0.40) ELANEXIAPMLXCMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 343 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2433138-B1 METHOD FOR DETECTING A WOUND INFECTION TECH UNIVERSITÄT GRAZ (AT) 2016-09-14 EP claimed
US-8822173-B2 Wound dressing or swab for detecting infection EVA WEHRSCHUTZ-SIGL (AT) 2014-09-02 US claimed
US-20130337484-A1 METHOD FOR DETECTING A WOUND INFECTION WEHRSCHUTZ-SIGL, EVA (AT) 2013-12-19 US claimed
US-8497085-B2 Method for detecting a wound infection TECHNISCHE UNIVERSITAT GRAZ (AT) 2013-07-30 US claimed
CN-102928586-A Method for detecting human neutrophil elastase based on nucleic acid aptamer UNIV SHANXI 2013-02-13 CN claimed
US-20120258483-A1 METHOD FOR DETECTING A WOUND INFECTION TECHNISCHE UNIVERSITAT GRAZ (AT) 2012-10-11 US claimed
EP-2433138-A1 METHOD FOR DETECTING A WOUND INFECTION Technische Universität Graz (AT) 2012-03-28 EP claimed
WO-2010133589-A1 METHOD FOR DETECTING A WOUND INFECTION TECHNISCHE UNIVERSITÄT GRAZ (AT) 2010-11-25 WO claimed
US-6740499-B2 DETECTING ELASTASE IN PATIENT SPUTUM THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK 2004-05-25 US claimed
US-20020001820-A1 Method for detecting bacterial exacerbations of chronic lung disease THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK 2002-01-03 US claimed
EP-3897669-B1 METHODS AND COMPOSITIONS RELATED TO THERAPEUTIC PEPTIDES FOR CANCER THERAPY UNIV CHICAGO (US) 2026-05-20 EP disclosed
US-12611443-B2 Methods and compositions related to therapeutic peptides for cancer therapy THE UNIVERSITY OF CHICAGO 2026-04-28 US disclosed
EP-4705336-A1 NOVEL THERAPEUTIC POLYPEPTIDE King, Paul Thomas (AU) 2026-03-11 EP disclosed
US-12516307-B2 Modified porcine pancreatic elastase proteins ONCHILLES PHARMA, INC. (US) 2026-01-06 US disclosed
EP-3873394-B1 SYSTEM FOR ANALYSIS OF BODY FLUIDS AND WOUND-ASSOCIATED BIOMOLECULES PROGENITEC INC (US) 2025-12-24 EP disclosed
EP-0205555-A4 SERINE PROTEASE INHIBITORS AND METHODS FOR ISOLATION OF SAME. SYNERGEN BIOLOG INC (US) 1987-11-09 EP disclosed
EP-0205555-A1 SERINE PROTEASE INHIBITORS AND METHODS FOR ISOLATION OF SAME. SYNERGEN BIOLOG INC (US) 1986-12-30 EP disclosed
WO-1986003497-A1 SERINE PROTEASE INHIBITORS AND METHODS FOR ISOLATION OF SAME SYNERGEN BIOLOGICALS, INC. (US) 1986-06-19 WO disclosed
EP-0169114-A2 Human alpha-1-antitrypin derivatives and process for their preparation TRANSGENE S.A. (FR) 1986-01-22 EP disclosed
WO-1986000337-A1 HUMAN alpha1-ANTITRYPSIN DERIVATIVES AND PREPARATION PROCESS THEREOF TRANSGENE S.A. (FR) 1986-01-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12611443-B2 Methods and compositions related to therapeutic peptides for cancer therapy ELANE, PREP, BRCA1 TACR1 3680/4885ELANE 1/4885FKBP4 2075/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.