Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL387694 | 0.91 | TACR1 (0.40) | KCNH2LMNATACR1CYP2C9CYP2C19 | |
| SCHEMBL2682605 | 0.86 | TACR1 (0.40) | KCNH2TACR1TRPV1FKBP4 | |
| SCHEMBL846697 | 0.86 | FKBP4 (0.51) | TACR1FKBP4 | |
| SCHEMBL7235515 | 0.81 | TACR1 (0.41) | LMNATACR1MAPK1TRPV1FKBP4 | |
| SCHEMBL8662040 | 0.81 | ELANE (0.40) | — | |
| SCHEMBL1451494 | 0.80 | MEN1 (0.40) | LMNAHTTALDH1A1MEN1KMT2A | |
| SCHEMBL535732 | 0.79 | ACE (0.40) | LMNA | |
| SCHEMBL1296384 | 0.79 | LMNA (0.48) | KCNH2LMNATACR1CYP2C9CYP2C19 | |
| SCHEMBL27824844 | 0.79 | LMNA (0.48) | KCNH2LMNATACR1CYP2C9CYP2C19 | |
| SCHEMBL1088354 | 0.79 | TACR1 (0.38) | TACR1KMT2AFKBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101211-B2 | Controlling moisture, elasticity of skin; using plant extracts; antiinflammatory agents; antiallergens | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2012-01-24 | — | — | US | disclosed |
| WO-2008078846-A1 | COSMETIC COMPOSITION FOR ANTI-AGING OF SKIN | SK CHEMICALS CO., LTD. (KR) | 2008-07-03 | — | — | WO | disclosed |
| US-20040028643-A1 | Compositions for retarding skin aging | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2004-02-12 | — | — | US | disclosed |
| EP-1352640-A1 | COMPOSITIONS FOR RETARDING SKIN AGING | Kabushiki Kaisha Yakult Honsha (JP) | 2003-10-15 | — | — | EP | disclosed |