Folic Acid

Folic Acid

SCHEMBL3877

Nc1nc2ncc(CNc3ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc3)nc2c(=O)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TYMS P04818 3/20 1.00
KDM4E B2RXH2 1/20 1.00
MEN1 O00255 1/20 1.00
ALDH1A1 P00352 1/20 1.00
POLB P06746 1/20 1.00
GAA P10253 1/20 1.00
AKR1B1 P15121 1/20 1.00
HPGD P15428 1/20 1.00
TSHR P16473 1/20 1.00
PTGS2 P35354 1/20 1.00
KMT2A Q03164 1/20 1.00
HSD17B10 Q99714 1/20 1.00
TDP1 Q9NUW8 1/20 1.00
ADORA3 P0DMS8 1/20 0.73
DHFR P00374 7/20 0.67
GART P22102 2/20 0.67
ATIC P31939 2/20 0.67
MTHFD1 P11586 1/20 0.57
MTHFD2 P13995 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Folic Acid SCHEMBL29441959 1.00 TYMS (1.00) TYMSKDM4EMEN1ALDH1A1POLB
Folic Acid SCHEMBL332170 1.00 TYMS (1.00) TYMSKDM4EMEN1ALDH1A1POLB
Folic Acid SCHEMBL29349485 1.00 TYMS (1.00) TYMSKDM4EMEN1ALDH1A1POLB
Folic Acid SCHEMBL29388311 1.00 TYMS (1.00) TYMSKDM4EMEN1ALDH1A1POLB
Folic Acid SCHEMBL16492117 1.00 TYMS (1.00) TYMSKDM4EMEN1ALDH1A1POLB
Folic Acid SCHEMBL248712 1.00 TYMS (1.00) TYMSKDM4EMEN1ALDH1A1POLB
Folic Acid SCHEMBL29357550 1.00 TYMS (1.00) TYMSKDM4EMEN1ALDH1A1POLB
Folic Acid SCHEMBL29624885 1.00 TYMS (1.00) TYMSKDM4EMEN1ALDH1A1POLB
Folic Acid SCHEMBL403054 1.00 TYMS (1.00) TYMSKDM4EMEN1ALDH1A1POLB
Folic Acid SCHEMBL27730431 1.00 TYMS (1.00) TYMSKDM4EMEN1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 337919 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119257253-A Use of nutritional compositions to aid in improving memory 飞鹤(阿鲁科尔沁旗)乳品有限公司 2025-01-07 CN claimed
US-12178855-B2 Compositions and methods for facilitating delivery of synthetic nucleic acids to cells TRANSLATE BIO MA, INC. (US) 2024-12-31 US claimed
WO-2024263607-A2 ULTRA-BRIGHT NANOPARTICLE FLUORESCENT DYE COMPLEXES CYTEK BIOSCIENCES, INC. (US) 2024-12-26 WO claimed
CN-113122605-B Culture medium for producing anti-CD 47 antibody and fermentation method 鲁南制药集团股份有限公司 2024-12-24 CN claimed
CN-116898047-B Compound feed for blue crabs and preparation method thereof 中国水产科学研究院南海水产研究所 2024-12-24 CN claimed
CN-112067674-B Molecularly imprinted electrochemical sensor and folic acid content detection method thereof 常州市新鸿医药化工技术有限公司 2024-12-20 CN claimed
CN-119144669-A Non-sterilization fermentation medium and fermentation method of clostridium tyrobutyricum 南京工业大学 2024-12-17 CN claimed
CN-119138479-A Formula milk powder and mixing method thereof 黑龙江飞鹤乳业有限公司 2024-12-17 CN claimed
EP-4472677-A1 THERAGNOSTIC FOLATE CONJUGATES Merck Patent GmbH (DE) 2024-12-11 EP claimed
EP-4472637-A1 TREATMENT OF HEMATOLOGICAL MALIGNANCIES WITH MENIN INHIBITORS AND P-GLYCOPROTEIN INHIBITORS Kura Oncology, Inc. (US) 2024-12-11 EP claimed
US-4058122-A Osmotic system with laminated wall formed of different materials ALZA CORPORATION (US) 1977-11-15 US claimed
US-4053593-A PREVENTING AND CURING DISEASES IN FISH FRUMOFF LEW 1977-10-11 US claimed
US-4049494-A Vaccine production process THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1977-09-20 US claimed
US-4042733-A Forming solid, adhesive-free composite of membrane filters and cellulosic cardboard BOEHRINGER INGELHEIM GMBH (DT) 1977-08-16 US claimed
US-4028465-A BUFFERS, STABILIZED WITH A DITHIO-POLYOL BIO-RAD LABORATORIES (US) 1977-06-07 US claimed
US-4001583-A COVALENTLY BOUND BIOLOGICAL SUBSTANCES TO PLASTIC MATERIALS AND USE IN RADIOASSAY BARRETT M JAMES 1977-01-04 US claimed
US-3989812-A Folic acid derivatives and use in radio-assay SMITHKLINE INSTRUMENTS, INC. (US) 1976-11-02 US claimed
US-3988431-A FOLIC ACID STANDARD BECTON, DICKINSON AND COMPANY (US) 1976-10-26 US claimed
US-3972991-A MEASUREMENT OF FOLATE IN A BLOOD SERUM CASE WESTERN RESERVE UNIVERSITY (US) 1976-08-03 US claimed
US-3960757-A HYDROPHOBIC TOYO JOZO CO., LTD. (JA) 1976-06-01 US claimed