Folic Acid

Folic Acid

SCHEMBL403054

Nc1nc2ncc(CNc3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc3)nc2c(=O)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TYMS P04818 3/20 1.00
KDM4E B2RXH2 1/20 1.00
MEN1 O00255 1/20 1.00
ALDH1A1 P00352 1/20 1.00
POLB P06746 1/20 1.00
GAA P10253 1/20 1.00
AKR1B1 P15121 1/20 1.00
HPGD P15428 1/20 1.00
TSHR P16473 1/20 1.00
PTGS2 P35354 1/20 1.00
KMT2A Q03164 1/20 1.00
HSD17B10 Q99714 1/20 1.00
TDP1 Q9NUW8 1/20 1.00
ADORA3 P0DMS8 1/20 0.73
DHFR P00374 7/20 0.67
GART P22102 2/20 0.67
ATIC P31939 2/20 0.67
MTHFD1 P11586 1/20 0.57
MTHFD2 P13995 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Folic Acid SCHEMBL29441959 1.00 TYMS (1.00) TYMSKDM4EMEN1ALDH1A1POLB
Folic Acid SCHEMBL332170 1.00 TYMS (1.00) TYMSKDM4EMEN1ALDH1A1POLB
Folic Acid SCHEMBL29349485 1.00 TYMS (1.00) TYMSKDM4EMEN1ALDH1A1POLB
Folic Acid SCHEMBL29388311 1.00 TYMS (1.00) TYMSKDM4EMEN1ALDH1A1POLB
Folic Acid SCHEMBL16492117 1.00 TYMS (1.00) TYMSKDM4EMEN1ALDH1A1POLB
Folic Acid SCHEMBL248712 1.00 TYMS (1.00) TYMSKDM4EMEN1ALDH1A1POLB
Folic Acid SCHEMBL29357550 1.00 TYMS (1.00) TYMSKDM4EMEN1ALDH1A1POLB
Folic Acid SCHEMBL3877 1.00 TYMS (1.00) TYMSKDM4EMEN1ALDH1A1POLB
Folic Acid SCHEMBL29624885 1.00 TYMS (1.00) TYMSKDM4EMEN1ALDH1A1POLB
Folic Acid SCHEMBL27730431 1.00 TYMS (1.00) TYMSKDM4EMEN1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2372 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4728876-A1 FOOD SUPPLEMENT SYSTEM AND USE air up group GmbH (DE) 2026-04-22 EP claimed
US-20250213501-A1 IMPROVING SEMEN QUALITY CEUTICS HEALTH GMBH (AT) 2025-07-03 US claimed
EP-3632345-B1 APPARATUS FOR FIXING INSTRUMENT WITHIN INTESTINAL CANAL JSR MEDICAL CO LTD (KR) 2025-07-02 EP claimed
CN-120154617-A Application of pteroylglutamic acid in preparing medicine for repairing intestinal barrier injury 中国药科大学 2025-06-17 CN claimed
WO-2025120243-A1 NUTRICOSMETIC PRODUCT THAT NATURALLY STIMULATES GROWTH HORMONE (HGH) PRODUCTION, ALLOWING AGING TO BE DELAYED CREALIZE HK SL (ES) 2025-06-12 WO claimed
EP-4503955-A1 IMPROVING SEMEN QUALITY Ceutics Health GmbH (AT) 2025-02-12 EP claimed
CN-119300728-A Improving semen quality 希尔迪克斯健康有限责任公司 2025-01-10 CN claimed
US-20250009355-A1 APPARATUS FOR FIXING INSTRUMENT WITHIN INTESTINAL CANAL JSR MEDICAL CO., LTD (KR) 2025-01-09 US claimed
US-20240325430-A1 MULTIPLE FOLATE FORMULATION AND USE THEREOF JAYMAC PHARMACEUTICAL LLC (US) 2024-10-03 US claimed
CN-118638761-A Ginsenoside transglycosidase, preparation method thereof and method for converting ginsenoside 三蚁科技(广州)有限公司 2024-09-13 CN claimed
US-20020052374-A1 Pharmaceutical preparation containing at least folic acid or a folate and tetrahydrobiopterin (bh4) or derivatives thereof used for treating or preventing cardiovascular or neurological disorders by modulating of the activity of nitric oxide synthase (nos) MERCK EPROVA AG (CH) 2002-05-02 US claimed
EP-0686263-B1 COMPETITIVE IMMUNOASSAY UTILIZING BINDING PROTEIN IN A MULTICLONAL ANTIBODY FORMAT ABBOTT LAB (US) 2001-04-18 EP claimed
US-6008221-A REDUCING HOMOCYSTEINE IN BLOOD LEVEL ON THE VASCULATURE OR ON NERVE CELLS IN THE BRAIN, DETOXIFICATION, TREATING NEURODEGENERATION BRISTOL-MYERS SQUIBB COMPANY (US) 1999-12-28 US claimed
EP-0951293-A1 METHOD FOR TREATING ALZHEIMER'S DISEASE BRISTOL-MYERS SQUIBB COMPANY (US) 1999-10-27 EP claimed
EP-0686263-A4 COMPETITIVE IMMUNOASSAY UTILIZING BINDING PROTEIN IN A MULTICLONAL ANTIBODY FORMAT ABBOTT LAB (US) 1998-06-10 EP claimed
WO-1998019690-A1 METHOD FOR TREATING ALZHEIMER'S DISEASE BRISTOL-MYERS SQUIBB COMPANY (US) 1998-05-14 WO claimed
WO-1997021444-A9 CYTOKINE AND HEMOPOIETIC FACTOR ENDOGENOUS PRODUCTION ENHANCER AND METHODS OF USE THEREOF 1997-10-30 WO claimed
EP-0686263-A1 COMPETITIVE IMMUNOASSAY UTILIZING BINDING PROTEIN IN A MULTICLONAL ANTIBODY FORMAT ABBOTT LABORATORIES (US) 1995-12-13 EP claimed
US-5434087-A Folate immunoassay utilizing folate binding protein in a multiclonal antibody format ABBOTT LABORATORIES (US) 1995-07-18 US claimed
WO-1994019695-A1 COMPETITIVE IMMUNOASSAY UTILIZING BINDING PROTEIN IN A MULTICLONAL ANTIBODY FORMAT ABBOTT LABORATORIES (US) 1994-09-01 WO claimed