Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.52 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6379741 | 0.78 | NR4A1 (0.59) | NR4A1NR4A2NR4A3PLK1MMP3 | |
| SCHEMBL6008119 | 0.77 | NR4A1 (0.57) | NR4A1NR4A2NR4A3PLK1MMP3 | |
| SCHEMBL6008108 | 0.77 | NR4A1 (0.57) | NR4A1NR4A2NR4A3PLK1MMP3 | |
| SCHEMBL32665708 | 0.76 | NR4A1 (0.61) | NR4A1NR4A2NR4A3PLK1MMP3 | |
| SCHEMBL5716814 | 0.76 | NR4A1 (0.61) | NR4A1NR4A2NR4A3PLK1MMP3 | |
| SCHEMBL15385197 | 0.76 | NR4A1 (0.61) | NR4A1NR4A2NR4A3PLK1MMP3 | |
| SCHEMBL2599098 | 0.74 | NR4A1 (0.59) | NR4A1NR4A2NR4A3PLK1MMP3 | |
| SCHEMBL7803256 | 0.74 | NR4A1 (0.59) | NR4A1NR4A2NR4A3PLK1MMP3 | |
| SCHEMBL732404 | 0.74 | NR4A1 (0.59) | NR4A1NR4A2NR4A3PLK1MMP3 | |
| SCHEMBL2599103 | 0.74 | NR4A1 (0.59) | NR4A1NR4A2NR4A3PLK1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563901-B2 | Intermediates of 2-substituted carbapenem derivatives and process for production thereof | MEIJI SEIKA KAISHA, LTD. (JP) | 2009-07-21 | — | — | US | disclosed |
| US-7524951-B2 | Intermediates of 2-substituted carbapenem derivatives and process for production thereof | MEIJI SEIKA KAISHA, LTD. (JP) | 2009-04-28 | — | — | US | disclosed |
| US-20090082571-A1 | Intermediates of 2-substituted carbapenem derivatives and process for production thereof | SASAKI TOSHIRO | 2009-03-26 | — | — | US | disclosed |
| US-20080167475-A1 | Intermediates of 2-substituted carbapenem derivatives and process for production thereof | SASAKI TOSHIRO | 2008-07-10 | — | — | US | disclosed |
| US-20080076917-A1 | Intermediates of 2-Substituted Carbapenem Derivatives and Process for Production Thereof | MEIJI SEIKA KAISHA, LTD. (JP) | 2008-03-27 | — | — | US | disclosed |
| EP-1582522-A1 | INTERMEDIATE FOR 2-SUBSTITUTED CARBAPENEM DERIVATIVE AND PRODUCTION PROCESS | MEIJI SEIKA KAISHA LTD. (JP) | 2005-10-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167475-A1 | Intermediates of 2-substituted carbapenem derivatives and process for production thereof | MGAM, G6PD, COASY | NR4A1 3567/4885NR4A2 3668/4885NR4A3 4128/4885 |
| US-20080076917-A1 | Intermediates of 2-Substituted Carbapenem Derivatives and Process for Production Thereof | MGAM, G6PD, COASY | NR4A1 3567/4885NR4A2 3668/4885NR4A3 4128/4885 |
| US-20090082571-A1 | Intermediates of 2-substituted carbapenem derivatives and process for production thereof | MGAM, G6PD, COASY | NR4A1 3567/4885NR4A2 3668/4885NR4A3 4128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.