Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2873819 | 1.00 | PNP (0.33) | PNPLMNASMN1; SMN2MTORALDH1A1 | |
| Phosphoric Acid SCHEMBL3691841 | 0.94 | PNP (0.32) | PNPLMNASMN1; SMN2MTORALDH1A1 | |
| SCHEMBL6886933 | 0.84 | PNP (0.33) | PNPLMNASMN1; SMN2MTORALDH1A1 | |
| SCHEMBL11134890 | 0.73 | PNP (0.38) | PNPLMNASMN1; SMN2MTORALDH1A1 | |
| SCHEMBL851105 | 0.56 | LGALS1 (0.44) | MEN1KMT2A | |
| SCHEMBL29114805 | 0.56 | LGALS1 (0.40) | MEN1KMT2A | |
| SCHEMBL10353319 | 0.56 | LGALS1 (0.40) | MEN1KMT2A | |
| SCHEMBL31601489 | 0.56 | LGALS1 (0.40) | MEN1KMT2A | |
| SCHEMBL29114803 | 0.56 | LGALS1 (0.40) | MEN1KMT2A | |
| SCHEMBL24243426 | 0.54 | LGALS1 (0.59) | LMNAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107109458-B | Cell-based defibrotide potency assay | 真蒂奥姆责任有限公司 | 2021-10-26 | — | — | CN | disclosed |
| EP-2107909-A2 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF LIVER DISORDERS | IDENIX Pharmaceuticals, Inc. (US) | 2009-10-14 | — | — | EP | disclosed |
| WO-2008082602-A2 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF LIVER DISORDERS | IDENIX PHARMACEUTICALS, INC. (US) | 2008-07-10 | — | — | WO | disclosed |
| EP-1439220-B1 | Immobilized biocatalysts usable for the manufacture of natural nucleosides and modified analogues through enzymatic transglycosylation reactions | ADORKEM TECHNOLOGY SPA (IT) | 2007-08-22 | — | — | EP | disclosed |
| US-20040142438-A1 | Novel immobilized biocatalysts usable for the production of natural nucleosides and modified analogues by enzymatic transglycosylation reactions | KERYOS SPA (IT) | 2004-07-22 | — | — | US | disclosed |
| EP-1439220-A1 | Immobilized biocatalysts usable for the manufacture of natural nucleosides and modified analogues through enzymatic transglycosylation reactions | Keryos Spa (IT) | 2004-07-21 | — | — | EP | disclosed |