Flufenisal

Flufenisal

SCHEMBL38781

CC(=O)Oc1ccc(-c2ccc(F)cc2)cc1C(=O)O

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFD P00746 2/20 0.81
KDM4E B2RXH2 5/20 0.56
HSD17B10 Q99714 4/20 0.56
ALDH1A1 P00352 3/20 0.56
TSHR P16473 3/20 0.56
PTGS1 P23219 2/20 0.56
PTGS2 P35354 2/20 0.56
HPGD P15428 2/20 0.56
ESR1 P03372 1/20 0.56
ITGB3 P05106 1/20 0.56
ITGA2B P08514 1/20 0.56
HMGB1 P09429 1/20 0.56
GGT1 P19440 1/20 0.56
BLM P54132 1/20 0.56
NAPRT Q6XQN6 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
LMNA P02545 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
MAPK1 P28482 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flufenisal SCHEMBL11333508 1.00 CFD (0.81) CFDKDM4EHSD17B10ALDH1A1TSHR
Flufenisal SCHEMBL3693207 0.98 CFD (0.79) CFDKDM4EHSD17B10ALDH1A1TSHR
Flufenisal SCHEMBL3695160 0.98 CFD (0.79) CFDKDM4EHSD17B10ALDH1A1TSHR
SCHEMBL11695642 0.94 CFD (0.72) CFDKDM4EHSD17B10ALDH1A1TSHR
SCHEMBL16715329 0.90 CFD (1.00) CFDKDM4EHSD17B10ALDH1A1TSHR
SCHEMBL10723672 0.87 CFD (0.87) CFDKDM4EHSD17B10ALDH1A1TSHR
SCHEMBL1162085 0.87 CFD (0.69) CFDKDM4EHSD17B10ALDH1A1TSHR
Flufenisal SCHEMBL3693206 0.86 CFD (0.59) CFDKDM4EHSD17B10ALDH1A1TSHR
SCHEMBL3695888 0.86 CFD (0.59) CFDKDM4EHSD17B10ALDH1A1TSHR
SCHEMBL10874988 0.86 CFD (0.59) CFDKDM4EHSD17B10ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11726 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3917907-B1 MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF UNIV DEGLI STUDI DI SALERNO (IT) 2025-05-21 EP claimed
EP-3441087-B1 METHODS OF TREATING CHRONIC PAIN TEVA PHARMACEUTICALS INT GMBH (CH) 2025-02-19 EP claimed
US-20240200072-A1 Allogeneic Cartilage Regeneration Tarachon, LLC (US) 2024-06-20 US claimed
EP-4308063-A1 PRE-FILLING SYSTEM TO ELIMINATE BUBBLES INSIDE CAPSULES HAVING A SOLID DOSAGE FORM Procaps SA (US) 2024-01-24 EP claimed
US-11771695-B2 Cannabinoid receptor modulators ARENA PHARMACEUTICALS, INC. (US) 2023-10-03 US claimed
EP-4185277-A1 SOFT SHELL GELATIN CAPSULES Procaps SA (US) 2023-05-31 EP claimed
US-20230125604-A1 ANTI-PACAP ANTIBODIES AND USES THEREOF H LUNDBECK AS (DK) 2023-04-27 US claimed
US-20230088240-A1 ACCELERATING THE DRYING RATE OF SOFTGEL CAPSULES GLAS AMERICAS LLC 2023-03-23 US claimed
US-11555064-B2 Treating headache comprising administering an antibody to calcitonin gene-related peptide TEVA PHARMACEUTICALS INTERNATIONAL GMBH (CH) 2023-01-17 US claimed
US-20220296529-A1 PRE-FILLING SYSTEM TO ELIMINATE BUBBLES INSIDE CAPSULES HAVING A SOLID DOSAGE FORMS WITHIN SAID CAPSULES GLAS AMERICAS LLC 2022-09-22 US claimed
WO-1985004589-A1 COUGH/COLD MIXTURES COMPRISING NON-STEROIDAL ANTI-INFLAMMATORY DRUGS SUNSHINE ABRAHAM 1985-10-24 WO claimed
WO-1985003443-A1 ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING DIPHENHYDRAMINE AND METHODS OF USING SAME RICHARDSON-VICKS, INC. (US) 1985-08-15 WO claimed
WO-1985002542-A1 ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME SUNSHINE ABRAHAM 1985-06-20 WO claimed
EP-0114886-A1 IMPROVED ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING CAFFEINE. SUNSHINE ABRAHAM (US) 1984-08-08 EP claimed
EP-0105635-A2 Nonirritating aqueous ophthalmic compositions comfort formulation for ocular therepeutic agents ALCON LABORATORIES, INC. (US) 1984-04-18 EP claimed
WO-1984000490-A1 IMPROVED ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING CAFFEINE AND METHODS OF USING SAME SUNSHINE ABRAHAM 1984-02-16 WO claimed
EP-0093520-A1 Pharmaceutical compositions and preparation thereof NORISTAN LIMITED (ZA) 1983-11-09 EP claimed
US-4376767-A ANTIBIOTICS AND PHARMACEUTICALS MERCK & CO., INC. (US) 1983-03-15 US claimed
EP-0055870-A1 Pyridylmethyl esters of selected bio-affecting carboxylic acids, process for preparing and pharmaceutical composition comprising the same MERCK & CO. INC. (US) 1982-07-14 EP claimed
EP-0051278-A1 Soft tertiary amine esters of bio-affecting carboxylic acids, processes for preparing and a pharmaceutical composition containing the same MERCK & CO. INC. (US) 1982-05-12 EP claimed