⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL153285 | 1.00 | — | — | |
| SCHEMBL3062521 | 1.00 | — | — | |
| Ammonia Solution, Strong SCHEMBL4910284 | 0.97 | CYP3A4 (0.46) | — | |
| SCHEMBL28114287 | 0.85 | CYP17A1 (0.53) | — | |
| SCHEMBL27083996 | 0.79 | CYP3A4 (0.44) | — | |
| SCHEMBL18810809 | 0.79 | CYP3A4 (0.44) | — | |
| SCHEMBL9331652 | 0.78 | NOS3 (0.54) | — | |
| SCHEMBL40655 | 0.78 | NOS3 (0.54) | — | |
| SCHEMBL9331061 | 0.78 | NOS3 (0.54) | — | |
| SCHEMBL9331190 | 0.78 | NOS3 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119776301-A | Alcohol dehydrogenase, recombinant genetically engineered bacterium and application thereof in asymmetric reduction of potential chiral carbonyl compounds | 杭州文德阶生物科技有限公司 | 2025-04-08 | — | — | CN | claimed |
| EP-0304706-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE COMPOUNDS HAVING PYRIDINE SKELETONS | CHISSO CORPORATION (JP) | 1992-11-19 | — | — | EP | claimed |
| US-4971909-A | TRANSESTERIFICATION IN THE PRESENCE OF HYDROLASES | CHISSO CORPORATION (JP) | 1990-11-20 | — | — | US | claimed |
| EP-0304706-A2 | Process for producing optically active compounds having pyridine skeletons | CHISSO CORPORATION (JP) | 1989-03-01 | — | — | EP | claimed |
| US-12577200-B2 | High-throughput method to rapidly add chemical moieties to a small molecule library | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2026-03-17 | — | — | US | disclosed |
| US-20250214984-A1 | COMPOUND HAVING KDM5 INHIBITORY ACTIVITY AND PHARMACEUTICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2025-07-03 | — | — | US | disclosed |
| EP-4146645-B1 | 3-AZABICYCLO(3.1.0)HEXANE DERIVATIVES HAVING KDM5 INHIBITORY ACTIVITY AND USE THEREOF | ONO PHARMACEUTICAL CO (JP) | 2025-06-25 | — | — | EP | disclosed |
| US-20250129067-A1 | PLATELET-DERIVED GROWTH FACTOR RECEPTOR (PDGFR) ALPHA INHIBITORS AND USES THEREOF | PROGENTOS THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | US | disclosed |
| US-12269817-B2 | Compound having KDM5 inhibitory activity and pharmaceutical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2025-04-08 | — | — | US | disclosed |
| CN-119776301-A | Alcohol dehydrogenase, recombinant genetically engineered bacterium and application thereof in asymmetric reduction of potential chiral carbonyl compounds | 杭州文德阶生物科技有限公司 | 2025-04-08 | — | — | CN | disclosed |
| EP-4471027-A1 | 3-AZABICYCLO(3.1.0)HEXANE DERIVATIVES HAVING KDM5 INHIBITORY ACTIVITY AND USE THEREOF | ONO Pharmaceutical Co., Ltd. (JP) | 2024-12-04 | — | — | EP | disclosed |
| CN-118475580-A | Platelet-derived growth factor receptor (PDGFR) alpha inhibitors and uses thereof | 普罗根托斯治疗公司 | 2024-08-09 | — | — | CN | disclosed |
| EP-0640072-A1 | SUBSTITUTED PYRIDINES, THEIR PREPARATION AND PHARMACEUTICAL USE | BTG INTERNATIONAL LIMITED (GB) | 1995-03-01 | — | — | EP | disclosed |
| EP-0336619-B1 | Optically active pyridylethanol derivatives | CHISSO CORP (JP) | 1995-02-22 | — | — | EP | disclosed |
| WO-1993023375-A1 | SUBSTITUTED PYRIDINES, THEIR PREPARATION AND PHARMACEUTICAL USE | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1993-11-25 | — | — | WO | disclosed |
| EP-0304706-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE COMPOUNDS HAVING PYRIDINE SKELETONS | CHISSO CORPORATION (JP) | 1992-11-19 | — | — | EP | disclosed |
| US-4971909-A | TRANSESTERIFICATION IN THE PRESENCE OF HYDROLASES | CHISSO CORPORATION (JP) | 1990-11-20 | — | — | US | disclosed |
| US-4965018-A | LIQUID CRYSTAL; HIGH TWISTABILITY, TEMPERTURE CHARACTERISTICS | CHISSO CORPORATION (JP) | 1990-10-23 | — | — | US | disclosed |
| EP-0336619-A2 | Optically active pyridylethanol derivatives | Chisso Corporation (JP) | 1989-10-11 | — | — | EP | disclosed |
| EP-0304706-A2 | Process for producing optically active compounds having pyridine skeletons | CHISSO CORPORATION (JP) | 1989-03-01 | — | — | EP | disclosed |