Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2832905 | 0.91 | TSHR (0.56) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL20829356 | 0.80 | ALDH1A1 (0.65) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL544745 | 0.79 | TSHR (0.60) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL4608703 | 0.79 | TSHR (0.60) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL4976681 | 0.79 | TSHR (0.60) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL29212545 | 0.79 | TSHR (0.60) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL8191937 | 0.79 | TSHR (0.60) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL8198631 | 0.79 | TSHR (0.60) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL277808 | 0.79 | — | — | |
| SCHEMBL15716951 | 0.79 | TSHR (0.65) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011140644-A1 | POLYACETAL OR POLYKETAL AND ETHER POLYMERS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2011-11-17 | — | — | WO | disclosed |