Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 19/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3879394 | 0.86 | HRH3 (0.44) | HRH3PIK3CG | |
| SCHEMBL3880490 | 0.84 | HRH3 (0.55) | HRH3 | |
| SCHEMBL3881397 | 0.83 | HRH3 (0.40) | HRH3 | |
| SCHEMBL3882084 | 0.81 | HRH3 (0.47) | HRH3HRH1 | |
| SCHEMBL3879149 | 0.81 | HRH3 (0.43) | HRH3PIK3CG | |
| SCHEMBL3880697 | 0.80 | HRH3 (0.39) | HRH3 | |
| SCHEMBL3882668 | 0.79 | HRH3 (0.38) | HRH3 | |
| SCHEMBL3879080 | 0.79 | HRH3 (0.40) | HRH3 | |
| SCHEMBL3878465 | 0.78 | HRH3 (0.41) | HRH3 | |
| SCHEMBL4039849 | 0.77 | HRH3 (0.48) | HRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858900-B1 | FUSED THIAZOLE DERIVATIVES HAVING AFFINITY FOR THE HISTAMINE H3 RECEPTOR | GLAXO GROUP LTD (GB) | 2009-01-07 | — | — | EP | claimed |