Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.48 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.38 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.38 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4032876 | 0.84 | HRH3 (0.42) | HRH3 | |
| SCHEMBL4032479 | 0.82 | HRH3 (0.53) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL4035015 | 0.79 | HRH3 (0.53) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| Hydrochloric Acid SCHEMBL4033620 | 0.78 | HRH3 (0.52) | HRH3L3MBTL3CHRM4L3MBTL1MBTD1 | |
| SCHEMBL16712257 | 0.77 | MAPT (0.48) | L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL4034608 | 0.77 | HRH3 (0.48) | HRH3L3MBTL3CHRM4L3MBTL1MBTD1 | |
| SCHEMBL3879396 | 0.77 | HRH3 (0.39) | HRH3HRH1 | |
| SCHEMBL4032017 | 0.76 | HRH3 (0.53) | HRH3HRH1KCNH2 | |
| SCHEMBL4033533 | 0.76 | HRH3 (0.56) | HRH3 | |
| SCHEMBL4031344 | 0.74 | HRH3 (0.42) | HRH3L3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1789410-B1 | METHYLENE DIPIPERIDINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2009-06-17 | — | — | EP | claimed |