SCHEMBL3879458

SCHEMBL3879458

CCCCCc1ccccc1N1C(=O)C=CC1=O

nearest known ligand 0.71

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 10/20 0.71
NR1H2 P55055 1/20 0.68
NR1H3 Q13133 1/20 0.68
TLR9 Q9NR96 1/20 0.52
FAAH O00519 2/20 0.51
LIPG Q9Y5X9 1/20 0.45
TSHR P16473 1/20 0.43
ALDH1A1 P00352 1/20 0.43
ALDH2 P05091 1/20 0.43
ALDH3A1 P30838 1/20 0.43
BID P55957 3/20 0.42
MCL1 Q07820 3/20 0.42
BCL2L1 Q07817 2/20 0.42
BAK1 Q16611 2/20 0.42
CES1 P23141 1/20 0.42
CDC25A P30304 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5711778 0.98 NR1H2 (0.70) MGLLNR1H2NR1H3TLR9FAAH
SCHEMBL3873448 0.95 MGLL (0.73) MGLLNR1H2NR1H3TLR9FAAH
SCHEMBL3774325 0.88 MGLL (0.79) MGLLNR1H2NR1H3TLR9FAAH
SCHEMBL30302472 0.88 MGLL (0.79) MGLLNR1H2NR1H3TLR9FAAH
SCHEMBL8352899 0.84 MGLL (0.77) MGLLNR1H2NR1H3TLR9FAAH
SCHEMBL29510771 0.84 MGLL (1.00) MGLLNR1H2NR1H3TLR9FAAH
SCHEMBL1535499 0.84 MGLL (1.00) MGLLNR1H2NR1H3TLR9FAAH
SCHEMBL1704226 0.83 MGLL (0.53) MGLLNR1H2NR1H3TLR9FAAH
SCHEMBL29378620 0.81 NR1H3 (1.00) MGLLNR1H2NR1H3LIPGALDH1A1
SCHEMBL8678686 0.81 MGLL (0.57) MGLLNR1H2NR1H3TLR9FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7476425-B2 Wide-viewing angle compensation film and transmission type liquid-crystal display employing the same TOSOH CORPORATION (JP) 2009-01-13 US disclosed
EP-1403297-B1 Transparent heat-resistant resin optical material and film TOSOH CORP (JP) 2007-03-28 EP disclosed
US-20060216436-A1 WIDE-VIEWING ANGLE COMPENSATION FILM AND TRANSMISSION TYPE LIQUID-CRYSTAL DISPLAY EMPLOYING THE SAME TOSOH CORPORATION (JP) 2006-09-28 US disclosed
US-7001967-B2 Resin with excellent heat resistance and dynamic characteristics, having negative birefringence and exhibiting a high refractive index and a high Abbe number, especially optical compensating members such as films, sheets and TOSOH CORPORATION (JP) 2006-02-21 US disclosed
US-20040190138-A1 Resin composition for optical film, optical film and process for producing the optical film TOSOH CORPORATION (JP) 2004-09-30 US disclosed
US-20040063887-A1 Transparent heat-resistant resin optical material and film TOSOH CORPORATION (JP) 2004-04-01 US disclosed
EP-1403297-A1 Transparent heat-resistant resin optical material and film Tosoh Corporation (JP) 2004-03-31 EP disclosed