Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.57 |
| ▸ | CNR2 | P34972 | 2/20 | 0.57 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 2/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 11/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25387193 | 0.86 | CNR1 (0.52) | CNR1CNR2MAP4K4KITPIK3CD | |
| SCHEMBL3888718 | 0.85 | CNR1 (0.44) | CNR1CNR2MAP4K4KITPOLB | |
| SCHEMBL3877546 | 0.80 | PIK3CD (0.59) | CNR1CNR2MAP4K4KITPIK3CD | |
| SCHEMBL30902260 | 0.77 | MAP4K4 (0.62) | CNR1CNR2MAP4K4KITPOLB | |
| SCHEMBL31029670 | 0.77 | MAP4K4 (0.62) | CNR1CNR2MAP4K4KITPOLB | |
| SCHEMBL30041443 | 0.77 | KIT (0.52) | CNR1CNR2MAP4K4KITPOLB | |
| SCHEMBL23932489 | 0.77 | KIT (0.52) | CNR1CNR2MAP4K4KITPOLB | |
| SCHEMBL11359394 | 0.77 | KIT (0.52) | CNR1CNR2MAP4K4KITPOLB | |
| SCHEMBL3874202 | 0.76 | KIT (0.52) | CNR1CNR2MAP4K4KITPIK3CD | |
| SCHEMBL23932471 | 0.76 | KIT (0.53) | CNR1CNR2MAP4K4KITPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |
| CN-100376573-C | Fused 1, 3-dihydro-imidazole ring compounds | EISAI CO LTD (JP) | 2008-03-26 | — | — | CN | disclosed |
| US-20060111362-A1 | 1,3-Dihydroimidazole ring compound | EISAI CO., LTD. (JP) | 2006-05-25 | — | — | US | disclosed |
| CN-1745080-A | 1,3-dihydroimidazole fused-ring compound | EISAI CO LTD (JP) | 2006-03-08 | — | — | CN | disclosed |
| EP-1568699-A1 | 1,3-DIHYDROIMIDAZOLE FUSED-RING COMPOUND | Eisai Co., Ltd. (JP) | 2005-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111362-A1 | 1,3-Dihydroimidazole ring compound | NR2C2, NR0B2, DPP4 | CNR1 560/4885CNR2 570/4885MAP4K4 3017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.