SCHEMBL387991

SCHEMBL387991

CCCC=CSC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9886596 1.00
SCHEMBL12361650 0.82
SCHEMBL386780 0.82
SCHEMBL386872 0.80
SCHEMBL11591213 0.78 FAAH (0.50)
SCHEMBL385644 0.78 FAAH (0.50)
SCHEMBL10864289 0.78 FAAH (0.50)
SCHEMBL387807 0.78 FAAH (0.50)
SCHEMBL387755 0.78 FAAH (0.50)
SCHEMBL11591214 0.78 FAAH (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11828759-B2 Method of diagnosis PETER MACCALLUM CANCER INSTITUTE (AU) 2023-11-28 US disclosed
US-11749377-B2 Method and electronic system for predicting at least one fitness value of a protein, related computer program product PEACCEL (FR) 2023-09-05 US disclosed
US-20230227838-A1 ENHANCED CELL SURVIVAL AGAINST BIOTIC AND ABIOTIC STRESSES THROUGH SALICYLICK ACID-INDUCED NPR1 CONDENSATES DUKE UNIVERSITY 2023-07-20 US disclosed
US-20230193329-A1 Compositions and Methods for Recombinant Biosynthesis of Cannabinoids WILLOW BIOSCIENCES, INC. (CA) 2023-06-22 US disclosed
US-11506670-B2 Method of genome-wide direct identification of electrophile-sensing targets CORNELL UNIVERSITY (US) 2022-11-22 US disclosed
US-11008282-B2 Bicyclic-compounds for use as a medicament, in particular for treatment of parkinson's disease KOESTER HUBERT (CH) 2021-05-18 US disclosed
US-10837026-B2 Drought and salt tolerant plants UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2020-11-17 US disclosed
US-20180370906-A1 NOVEL BICYCLIC-COMPOUNDS FOR USE AS A MEDICAMENT, IN PARTICULAR FOR TREATMENT OF PARKINSON'S DISEASE Koester, Hubert (CH) 2018-12-27 US disclosed
US-20160326542-A1 DROUGHT AND SALT TOLERANT PLANTS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 2016-11-10 US disclosed
US-8101650-B2 Method for treating a immunology-related disease DAIICHI SANKYO COMPANY, LIMITED (JP) 2012-01-24 US disclosed
EP-1465869-A4 MODULATORS OF LXR X CEPTOR THERAPEUTICS INC (US) 2005-12-28 EP disclosed
US-6964976-B2 Amino alcohol derivatives SANKYO COMPANY, LIMITED (JP) 2005-11-15 US disclosed
US-20050043386-A1 Amino alcohol derivatives or phosphonic acid derivatives and pharmaceutical compositions containing these SANKYO COMPANY, LIMITED (JP) 2005-02-24 US disclosed
EP-1471054-A1 AMINO ALCOHOL DERIVATIVE OR PHOSPHONIC ACID DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THESE Sankyo Company, Limited (JP) 2004-10-27 EP disclosed
EP-1465869-A1 MODULATORS OF LXR X-Ceptor Therapeutics, Inc. (US) 2004-10-13 EP disclosed
US-20040132784-A1 Amino alcohol derivatives SANKYO COMPANY, LIMITED (JP) 2004-07-08 US disclosed
US-20030236297-A1 Amino alcohol derivatives SANKYO COMPANY, LIMITED (JP) 2003-12-25 US disclosed
US-20030181420-A1 Heterocyclic compounds, in particular N-substituted pyridones for modulating the activity of nuclear receptors EXELIXIS, INC. 2003-09-25 US disclosed
WO-2003059884-A1 MODULATORS OF LXR X-CEPTOR THERAPEUTICS, INC. (US) 2003-07-24 WO disclosed
EP-1300405-A1 AMINO ALCOHOL DERIVATIVES Sankyo Company, Limited (JP) 2003-04-09 EP disclosed