SCHEMBL3879952

SCHEMBL3879952

COC(=O)c1ccc2cc(OCCOc3ccc4cc(C(=O)OC)ccc4c3)ccc2c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.71
RAB9A P51151 1/20 0.63
PTPN11 Q06124 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
HGFAC Q04756 1/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
LCK P06239 1/20 0.51
KDM4E B2RXH2 2/20 0.50
ALOX15 P16050 1/20 0.50
HTT P42858 1/20 0.50
PPARG P37231 1/20 0.49
PPARD Q03181 1/20 0.49
PPARA Q07869 1/20 0.49
CA12 O43570 1/20 0.49
CA7 P43166 1/20 0.49
XDH P47989 1/20 0.49
CA9 Q16790 1/20 0.49
CA14 Q9ULX7 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5693928 0.92 MAPT (0.60) MAPTRAB9APTPN11TDP1L3MBTL1
SCHEMBL14548509 0.92 MAPT (0.60) MAPTRAB9APTPN11L3MBTL1KDM4E
SCHEMBL7339443 0.89 MAPT (0.57) MAPTRAB9APTPN11L3MBTL1HGFAC
SCHEMBL15460095 0.88 MAPT (0.54) MAPTRAB9APTPN11HGFACCA1
SCHEMBL8134959 0.88 ALDH1A1 (0.62) MAPTRAB9AKDM4EALDH1A1LMNA
SCHEMBL7333412 0.88 MAPT (0.55) MAPTRAB9APTPN11L3MBTL1HGFAC
SCHEMBL14299760 0.87 MAPT (0.53) MAPTRAB9APTPN11HGFACCA1
SCHEMBL15693341 0.85 MAPT (0.56) MAPTRAB9AHGFACLMNASMN1; SMN2
SCHEMBL8184959 0.85 EBP (0.54) MAPTLMNA
SCHEMBL29625647 0.85 EBP (0.54) MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2009143829-A METHOD FOR RECYCLING POLYESTER WASTE PRODUCT TEIJIN LTD 2009-07-02 JP disclosed
US-4581438-A Aromatic polyester of 6,6'-(ethylenedioxy)di-2-naphthoic acid, process for production thereof and film, fiber and other shaped articles therefrom TEIJIN LIMITED (JP) 1986-04-08 US disclosed
EP-0151299-A2 Aromatic polyester, process for production thereof and film, fiber and other shaped articles therefrom TEIJIN LIMITED (JP) 1985-08-14 EP disclosed