SCHEMBL3880118

SCHEMBL3880118

C[C@]1(O)CO[C@H]2[C@H]1OC[C@@]2(C)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3207308 1.00
SCHEMBL1723855 0.75
SCHEMBL23081620 0.71 THRB (0.42)
SCHEMBL15696573 0.71
SCHEMBL10016801 0.71 THRB (0.42)
SCHEMBL18837971 0.70
SCHEMBL10016813 0.69
SCHEMBL4296114 0.67
SCHEMBL12930415 0.67
SCHEMBL12899797 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4322359-A Process for the preparation of 2,5-dimethyl-1,4: 3,6-dianhydrosorbitol AMERICAN CYANAMID COMPANY (US) 1982-03-30 US claimed
EP-1682088-B1 ORAL MICROEMULSION COMPOSITION COMPRISING BIPHENYLDIMETHYLDICARBOXYLATE AND SILYBIN HANMI PHARM IND CO LTD (KR) 2013-04-03 EP disclosed
US-7485326-B2 Oral microemulsion composition comprising biphenyldimethyldicarboxylate and silybin HANMI PHARM CO., LTD. (KR) 2009-02-03 US disclosed
US-20070141185-A1 Oral microemulsion composition comprising biphenydimethyldicarboxylate and silybin HANMI PHARM. CO., LTD. (KR) 2007-06-21 US disclosed
EP-1682088-A1 ORAL MICROEMULSION COMPOSITION COMPRISING BIPHENYLDIMETHYLDICARBOXYLATE AND SILYBIN Hanmi Pharm. Co., Ltd. (KR) 2006-07-26 EP disclosed
WO-2005037249-A1 ORAL MICROEMULSION COMPOSITION COMPRISING BIPHENYLDIMETHYLDICARBOXYLATE AND SILYBIN HANMI PHARM. CO., LTD. (KR) 2005-04-28 WO disclosed
EP-1035862-B1 CYCLOSPORIN-CONTAINING MICROEMULSION PRECONCENTRATE COMPOSITION CHONG KUN DANG PHARM CORP (KR) 2003-07-09 EP disclosed
EP-0650721-B1 Cyclosporin soft capsule HANMI PHARM IND CO LTD (KR) 2000-09-13 EP disclosed
US-6063762-A CYCLOSPORIN MICROEMULSION WITH OILS, SOLVENTS AND SURFACTANTS CHONG KUN DANG CORP. (KR) 2000-05-16 US disclosed
US-6028067-A AS IMMUNOSUPPRESSANT CHONG KUN DANG CORP. (KR) 2000-02-22 US disclosed
US-5980939-A A CONCENTRATE EMULSION COMPRISING PROPYLENE CARBONATE, POLOXAMER, A GLYCERIDE AND SURFACTANT; FORMING SOFT CAPSULES WITH NO SOLVENT; NONTOXIC CHONG KUN DANG CORP. (KR) 1999-11-09 US disclosed
WO-1997036610-A1 CYCLOSPORIN-CONTAINING PHARMACEUTICAL COMPOSITION CHONG KUN DANG CORP. (KR) 1997-10-09 WO disclosed
US-5639474-A Cyclosporin soft capsule composition HANMI PHARM. IND., LTD. (KR) 1997-06-17 US disclosed
EP-0650721-A1 Cyclosporin soft capsule HANMI PHARM. IND. CO., LTD. (KR) 1995-05-03 EP disclosed