Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592196 | 1.00 | REN (0.66) | RENCYP3A4 | |
| SCHEMBL3562160 | 0.90 | REN (0.62) | REN | |
| SCHEMBL3562165 | 0.90 | REN (0.62) | REN | |
| SCHEMBL3562162 | 0.90 | REN (0.62) | REN | |
| SCHEMBL3880020 | 0.88 | REN (0.60) | RENCYP3A4 | |
| SCHEMBL4297917 | 0.86 | REN (0.89) | RENCYP3A4 | |
| SCHEMBL4297912 | 0.86 | REN (0.89) | RENCYP3A4 | |
| SCHEMBL4296191 | 0.86 | REN (0.89) | RENCYP3A4 | |
| SCHEMBL4297915 | 0.86 | REN (0.89) | RENCYP3A4 | |
| SCHEMBL2850288 | 0.85 | REN (0.49) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007117482-A2 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-10-18 | — | — | WO | claimed |
| EP-2010488-A2 | RENIN INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007117482-A2 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-10-18 | — | — | WO | disclosed |
| WO-2007117559-A2 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-10-18 | — | — | WO | disclosed |