Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA5A | P35218 | 4/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7132265 | 0.84 | CYP1A2 (0.46) | CYP1A2CYP2C19ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6551413 | 0.82 | KMT2A (0.50) | CYP1A2CYP2C19ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6550640 | 0.81 | KMT2A (0.47) | CYP1A2CYP2C19ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6550776 | 0.81 | KMT2A (0.49) | CYP1A2CYP2C19ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6549184 | 0.80 | KMT2A (0.46) | CYP1A2CYP2C19ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6550605 | 0.80 | ALDH1A1 (0.51) | CYP1A2CYP2C19ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6548726 | 0.80 | KMT2A (0.48) | CYP1A2CYP2C19ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6551184 | 0.79 | KMT2A (0.47) | CYP1A2CYP2C19ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6549727 | 0.79 | ALDH1A1 (0.50) | CYP1A2CYP2C19ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6551055 | 0.79 | KDM4E (0.47) | CYP1A2CYP2C19ALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638261-B2 | Radiation-sensitive resin composition | JSR CORPORATION (JP) | 2009-12-29 | — | — | US | disclosed |
| US-20090148790-A1 | RADIATION-SENSITIVE RESIN COMPOSITION | JSR CORPORATION (JP) | 2009-06-11 | — | — | US | disclosed |
| US-7521169-B2 | Radiation-sensitive resin composition | JSR CORPORATION (JP) | 2009-04-21 | — | — | US | disclosed |
| US-20060234153-A1 | Radiation-sensitive resin composition | JSR CORPORATION (JP) | 2006-10-19 | — | — | US | disclosed |
| EP-1557718-A1 | RADIATION-SENSITIVE RESIN COMPOSITION | JSR Corporation (JP) | 2005-07-27 | — | — | EP | disclosed |
| US-20030219680-A1 | Photoresists useful for microfabrication utilizing deep ultraviolet rays such as an excimer laser, x-rays such as synchrotron radiation, and electron beams | JSR CORPORATION (JP) | 2003-11-27 | — | — | US | disclosed |