Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 8/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.35 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.35 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.35 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.35 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.35 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3882348 | 0.99 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4DENPP2 | |
| SCHEMBL3888826 | 0.87 | PTGER1 (0.39) | PTGER1PTGER4PTGER3PTGER2BRD4 | |
| SCHEMBL3883505 | 0.85 | ITGB1 (0.41) | PDE4APDE4BPDE4CPDE4DENPP2 | |
| SCHEMBL3884350 | 0.85 | FFAR4 (0.41) | PDE4APDE4BPDE4CPDE4DRXRA | |
| SCHEMBL3883275 | 0.84 | THRA (0.42) | PDE4APDE4BPDE4CPDE4DRXRA | |
| SCHEMBL3896115 | 0.82 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4DENPP2 | |
| SCHEMBL3880942 | 0.81 | PDE4B (0.40) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3893026 | 0.81 | GRM2 (0.40) | PDE4APDE4BPDE4CPDE4DADRB1 | |
| SCHEMBL3883911 | 0.81 | KDM4E (0.40) | PDE4APDE4BPDE4CPDE4DITGB1 | |
| SCHEMBL3888282 | 0.81 | GRM2 (0.39) | PDE4APDE4BPDE4CPDE4DITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |