Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25144741 | 0.88 | ALDH1A1 (0.55) | ALDH1A1LMNAMEN1KMT2ATHRA | |
| SCHEMBL23334164 | 0.85 | ALDH1A1 (0.58) | ALDH1A1LMNAMEN1KMT2ATHRA | |
| SCHEMBL287047 | 0.85 | ALDH1A1 (0.41) | ALDH1A1LMNAMEN1KMT2ATHRA | |
| SCHEMBL23385619 | 0.83 | ALDH1A1 (0.47) | ALDH1A1LMNAMEN1KMT2ATHRA | |
| SCHEMBL30060774 | 0.83 | ALDH1A1 (0.47) | ALDH1A1LMNAMEN1KMT2ATHRA | |
| SCHEMBL17873261 | 0.76 | RXFP1 (0.41) | LMNAPOLBRXFP1PRMT5WDR77 | |
| SCHEMBL31546221 | 0.76 | ALDH1A1 (0.39) | ALDH1A1LMNAMEN1KMT2ATHRA | |
| SCHEMBL27734481 | 0.75 | NPC1 (0.66) | LMNAPOLBRXFP1PRMT5WDR77 | |
| SCHEMBL24576671 | 0.74 | RXFP1 (0.40) | ALDH1A1LMNAMEN1KMT2ATHRA | |
| SCHEMBL8058887 | 0.74 | RXFP1 (0.44) | LMNAPOLBRXFP1PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2084125-A1 | AMINOBENZOCYCLOHEPTENE DERIVATIVES, METHODS FOR PREPARING THE SAME AND USES THEREOF IN THERAPY | Universite De Haute Alsace (FR) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008059141-A1 | AMINOBENZOCYCLOHEPTENE DERIVATIVES, METHODS FOR PREPARING THE SAME AND USES THEREOF IN THERAPY | UNIVERSITE DE HAUTE ALSACE (FR) | 2008-05-22 | — | — | WO | disclosed |