SCHEMBL388186

SCHEMBL388186

NCCCC[C@@H](C(=O)O)N(CC(=O)O)CC(=O)O.[NaH].[NaH]

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.47
RNPEP Q9H4A4 1/20 0.46
CPB2 Q96IY4 7/20 0.42
FOLH1 Q04609 1/20 0.40
CYP2D6 P10635 1/20 0.39
NFKB1 P19838 1/20 0.39
BLM P54132 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
LMNA P02545 2/20 0.38
THRB P10828 2/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
PLG P00747 1/20 0.38
ALOX15 P16050 1/20 0.38
SLC6A2 P23975 1/20 0.38
RECQL P46063 1/20 0.38
SLC6A3 Q01959 1/20 0.38
GABRR1 P24046 2/20 0.35
GABRR3 A8MPY1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7166159 1.00 GSR (0.47) GSRRNPEPCPB2FOLH1CYP2D6
SCHEMBL382017 0.98 GSR (0.48) GSRRNPEPCPB2FOLH1CYP2D6
SCHEMBL24075891 0.98 GSR (0.48) GSRRNPEPCPB2FOLH1CYP2D6
SCHEMBL14890176 0.98 GSR (0.48) GSRRNPEPCPB2FOLH1CYP2D6
SCHEMBL158632 0.98 GSR (0.48) GSRRNPEPCPB2FOLH1CYP2D6
SCHEMBL7107141 0.96 GSR (0.47) GSRRNPEPCPB2FOLH1CYP2D6
Water SCHEMBL28962316 0.96 GSR (0.47) GSRRNPEPCPB2FOLH1CYP2D6
Water SCHEMBL1007984 0.96 GSR (0.47) GSRRNPEPCPB2FOLH1CYP2D6
SCHEMBL6270473 0.96 GSR (0.47) GSRRNPEPCPB2FOLH1CYP2D6
SCHEMBL7069551 0.89 GSR (0.41) GSRRNPEPCPB2FOLH1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2350659-B1 Method of culturing hepatocytes CORNING INC (US) 2016-11-02 EP disclosed
US-8465972-B2 Nanoparticulate cell culture surface CORNING INCORPORATED (US) 2013-06-18 US disclosed
US-8460923-B2 Affinity hydrogel and label independent detection methods thereof CORNING INCORPORATED (US) 2013-06-11 US disclosed
US-8338165-B2 Nanoparticulate cell culture surface CORNING INCORPORATED (US) 2012-12-25 US disclosed
US-20120288939-A1 NANOPARTICULATE CELL CULTURE SURFACE BAKER WENDY A (US) 2012-11-15 US disclosed
EP-2192410-B1 Nanoparticulate affininty capture for label independent detections system CORNING INC (US) 2012-07-11 EP disclosed
US-20120045772-A1 Affinity Hydrogel and Label Independent Detection Methods Thereof CORNING INCORPORATED 2012-02-23 US disclosed
US-8101405-B2 Nanoparticulate affinity capture for label independent detection system CORNING INCORPORATED (US) 2012-01-24 US disclosed
EP-2362220-A1 Affinity hydrogel and label independent detection methods thereof Corning Incorporated (US) 2011-08-31 EP disclosed
EP-2350659-A2 NANOPARTICULATE CELL CULTURE SURFACE Corning Incorporated (US) 2011-08-03 EP disclosed
US-20100159499-A1 NANOPARTICULATE CELL CULTURE SURFACE CORNING INCORPORATED 2010-06-24 US disclosed
WO-2010062801-A1 NANOPARTICULATE AFFINITY CAPTURE FOR LABEL INDEPENDENT DETECTION SYSTEM CORNING INCORPORATED (US) 2010-06-03 WO disclosed
WO-2010062935-A2 NANOPARTICULATE CELL CULTURE SURFACE CORNING INCORPORATED (US) 2010-06-03 WO disclosed
EP-2192410-A1 Nanoparticulate affininty capture for label independent detections system CORNING INCORPORATED (US) 2010-06-02 EP disclosed
US-20100129911-A1 Nanoparticulate Affinity Capture for Label Independent Detection System CORNING INCORPORATED 2010-05-27 US disclosed