Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.38 |
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.38 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.38 |
| ▸ | HDAC3 known ✓ | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 known ✓ | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 known ✓ | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 known ✓ | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 known ✓ | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 known ✓ | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 known ✓ | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 known ✓ | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 known ✓ | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 known ✓ | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 known ✓ | Q9UQL6 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.47 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 7/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28962316 | 1.00 | GSR (0.47) | GSRRNPEPCPB2FOLH1CYP2D6 | |
| SCHEMBL24075891 | 0.98 | GSR (0.48) | GSRRNPEPCPB2FOLH1CYP2D6 | |
| SCHEMBL14890176 | 0.98 | GSR (0.48) | GSRRNPEPCPB2FOLH1CYP2D6 | |
| SCHEMBL158632 | 0.98 | GSR (0.48) | GSRRNPEPCPB2FOLH1CYP2D6 | |
| SCHEMBL382017 | 0.98 | GSR (0.48) | GSRRNPEPCPB2FOLH1CYP2D6 | |
| SCHEMBL6270473 | 0.96 | GSR (0.47) | GSRRNPEPCPB2FOLH1CYP2D6 | |
| SCHEMBL7107141 | 0.96 | GSR (0.47) | GSRRNPEPCPB2FOLH1CYP2D6 | |
| SCHEMBL388186 | 0.96 | GSR (0.47) | GSRRNPEPCPB2FOLH1CYP2D6 | |
| SCHEMBL7166159 | 0.96 | GSR (0.47) | GSRRNPEPCPB2FOLH1CYP2D6 | |
| SCHEMBL387410 | 0.92 | GSR (0.41) | GSRRNPEPCPB2FOLH1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119351395-A | Method for synthesizing D-psicose by multienzyme co-immobilization cascade | 江南大学 | 2025-01-24 | — | — | CN | claimed |
| CN-116482067-A | Aptamer functionalized magnetic nano probe based on multilayer organic metal framework-nano Jin Jie guide and preparation method thereof | 福州大学 | 2023-07-25 | — | — | CN | claimed |
| US-20190118174-A1 | MICROFLUIDICS FOR ANALYTE DETECTION BASED ON THE LIGHT TO HEAT CONVERSION PROPERTIES OF METAL NANOPARTICLES | NANOIMMUNOTECH S L (ES) | 2019-04-25 | — | — | US | claimed |
| EP-3436193-A1 | MICROFLUIDICS FOR ANALYTE DETECTION BASED ON THE LIGHT TO HEAT CONVERSION PROPERTIES OF METAL NANOPARTICLES | Nanoimmunotech, S.L. (ES) | 2019-02-06 | — | — | EP | claimed |
| WO-2017167769-A1 | MICROFLUIDICS FOR ANALYTE DETECTION BASED ON THE LIGHT TO HEAT CONVERSION PROPERTIES OF METAL NANOPARTICLES | NANOIMMUNOTECH, S.L. (ES) | 2017-10-05 | — | — | WO | claimed |
| US-9045513-B2 | Method for preparing precursor used for labeling hepatocyte receptor and containing trisaccharide and DTPA ligand | Atomic Energy Council—Institute of Nuclear Energy Research (TW) | 2015-06-02 | — | — | US | claimed |
| US-20140046045-A1 | METHOD FOR PREPARING PRECURSOR USED FOR LABELING HEPATOCYTE RECEPTOR AND CONTAINING TRISACCHARIDE AND DTPA LIGAND | ATOMIC ENERGY COUNCIL - INSTITUTE OF NUCLEAR ENERGY RESEARCH (TW) | 2014-02-13 | — | — | US | claimed |
| WO-2025224047-A1 | FUNCTIONALIZATION OF PEGYLATED SURFACE | STICHTING RADBOUD UNIVERSITEIT (NL) | 2025-10-30 | — | — | WO | disclosed |
| US-20250262566-A1 | DEVICE FOR SEPARATING AN ANALYTE FROM OTHER COMPONENTS IN AN ELECTROLYTIC SOLUTION | NYCTEA TECH AB (SE) | 2025-08-21 | — | — | US | disclosed |
| CN-119351395-A | Method for synthesizing D-psicose by multienzyme co-immobilization cascade | 江南大学 | 2025-01-24 | — | — | CN | disclosed |
| CN-119351391-A | Method for efficiently immobilizing enzyme and application of method in preparation of D-psicose | 江南大学 | 2025-01-24 | — | — | CN | disclosed |
| CN-118866396-A | Method for evaluating damage of Maillard reaction product to body immune system | 黑龙江飞鹤乳业有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-118858558-A | Method for evaluating damage of Maillard reaction product to body nervous system | 黑龙江飞鹤乳业有限公司 | 2024-10-29 | — | — | CN | disclosed |
| EP-1421371-A1 | BIOSENSOR | Duke University (US) | 2004-05-26 | — | — | EP | disclosed |
| WO-2003072143-A9 | COMPOSITIONS FOR DELIVERY OF THERAPEUTICS AND OTHER MATERIALS, AND METHODS OF MAKING AND USING THE SAME | PHARMAIN LTD (US) | 2004-03-04 | — | — | WO | disclosed |
| US-20030224974-A1 | Compositions for delivery of therapeutics and other materials, and methods of making and using the same | PHARMAIN CORPORATION | 2003-12-04 | — | — | US | disclosed |
| WO-2003072143-A1 | COMPOSITIONS FOR DELIVERY OF THERAPEUTICS AND OTHER MATERIALS, AND METHODS OF MAKING AND USING THE SAME | PHARMAIN, LTD. (US) | 2003-09-04 | — | — | WO | disclosed |
| US-20030129622-A1 | Biosensor | NAVY, SECRETARY OF THE UNITED | 2003-07-10 | — | — | US | disclosed |
| WO-2003021247-A1 | BIOSENSOR | DUKE UNIVERSITY (US) | 2003-03-13 | — | — | WO | disclosed |
| US-20030032043-A1 | Latex based adsorbent chip | CIPHERGEN BIOSYSTEMS, INC. | 2003-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046045-A1 | METHOD FOR PREPARING PRECURSOR USED FOR LABELING HEPATOCYTE RECEPTOR AND CONTAINING TRISACCHARIDE AND DTPA LIGAND | HDGF, NR1H4, TRHR | THRB 128/4885MEN1 4360/4885SLC6A2 3097/4885 |
| US-20030224974-A1 | Compositions for delivery of therapeutics and other materials, and methods of making and using the same | TFRC, ANXA6, TTPA | THRB 3238/4885MEN1 1554/4885SLC6A2 904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.