Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 7/20 | 0.39 |
| ▸ | YES1 | P07947 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3886531 | 0.92 | C5AR1 (0.41) | KEAP1NFE2L2C5AR1SRCYES1 | |
| SCHEMBL3895970 | 0.91 | SCN9A (0.39) | KEAP1NFE2L2C5AR1SRCYES1 | |
| SCHEMBL3884439 | 0.90 | C5AR1 (0.42) | KEAP1NFE2L2C5AR1SRCYES1 | |
| SCHEMBL3894528 | 0.89 | BRD4 (0.46) | BRD4SRC | |
| SCHEMBL3894580 | 0.88 | C5AR1 (0.44) | KEAP1NFE2L2C5AR1SRCYES1 | |
| SCHEMBL3894647 | 0.87 | C5AR1 (0.48) | KEAP1NFE2L2C5AR1SRCYES1 | |
| SCHEMBL3883511 | 0.86 | BRD4 (0.39) | BRD4KEAP1NFE2L2C5AR1SRC | |
| SCHEMBL3882579 | 0.86 | IKBKB (0.40) | BRD4KEAP1NFE2L2C5AR1SRC | |
| SCHEMBL3682868 | 0.86 | FFAR4 (0.43) | BRD4EP300C5AR1CNR1SRC | |
| SCHEMBL3882409 | 0.86 | PTGER1 (0.42) | KEAP1NFE2L2C5AR1SRCYES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |