Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 13/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3882579 | 0.92 | IKBKB (0.40) | BRD4PTGDR2SRC | |
| SCHEMBL3884083 | 0.91 | RORC (0.39) | BRD4PTGDR2SRC | |
| SCHEMBL3883511 | 0.91 | BRD4 (0.39) | BRD4PTGDR2SRC | |
| SCHEMBL3882287 | 0.89 | BRD4 (0.41) | BRD4SRC | |
| SCHEMBL3882409 | 0.88 | PTGER1 (0.42) | SRC | |
| SCHEMBL3890246 | 0.87 | PTGER1 (0.40) | SRC | |
| SCHEMBL3884439 | 0.86 | C5AR1 (0.42) | SRC | |
| SCHEMBL3881996 | 0.86 | KEAP1 (0.40) | SRC | |
| SCHEMBL3883892 | 0.86 | SRC (0.40) | SRC | |
| SCHEMBL3886531 | 0.86 | C5AR1 (0.41) | SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |