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Sugi Predict / Compounds / SCHEMBL3882834

SCHEMBL3882834

SCHEMBL3882834

Cc1ccc(-c2ccc(S(=O)(=O)Nc3cc(N4CC(C)NC(C)C4)ccn3)cc2F)o1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3533970 1.00 GHSR (1.00) GHSR
Hydrochloric Acid SCHEMBL3545031 0.99 GHSR (0.98) GHSR
SCHEMBL3543397 0.87 GHSR (1.00) GHSR
SCHEMBL3543400 0.87 GHSR (1.00) GHSR
SCHEMBL4802847 0.83 GHSR (1.00) GHSR
SCHEMBL3539578 0.83 GHSR (1.00) GHSR
SCHEMBL3544041 0.83 GHSR (0.71) GHSR
SCHEMBL3544036 0.83 GHSR (0.71) GHSR
SCHEMBL3539576 0.83 GHSR (1.00) GHSR
SCHEMBL4802833 0.83 GHSR (1.00) GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2013178-A1 PIPERAZINE DERIVATIVES AS GROWTH HORMONE SECRETAGOGUE (GHS) RECEPTOR AGONISTS GLAXO GROUP LIMITED (GB) 2009-01-14 — — EP claimed
WO-2007113202-A1 PIPERAZINE DERIVATIVES AS GROWTH HORMONE SECRETAGOGUE (GHS) RECEPTOR AGONISTS GLAXO GROUP LIMITED (GB) 2007-10-11 — — WO claimed
EP-2013178-A1 PIPERAZINE DERIVATIVES AS GROWTH HORMONE SECRETAGOGUE (GHS) RECEPTOR AGONISTS GLAXO GROUP LIMITED (GB) 2009-01-14 — — EP disclosed
WO-2007113202-A1 PIPERAZINE DERIVATIVES AS GROWTH HORMONE SECRETAGOGUE (GHS) RECEPTOR AGONISTS GLAXO GROUP LIMITED (GB) 2007-10-11 — — WO disclosed