Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.31 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3009810 | 0.98 | ACHE (0.38) | ACHETSHRALDH1A1CA1CA2 | |
| SCHEMBL4480 | 0.85 | TSHR (0.53) | ACHETSHRALDH1A1CA1CA2 | |
| SCHEMBL3127305 | 0.85 | TSHR (0.53) | ACHETSHRALDH1A1CA1CA2 | |
| SCHEMBL29357701 | 0.85 | TSHR (0.53) | ACHETSHRALDH1A1CA1CA2 | |
| SCHEMBL1991572 | 0.83 | TSHR (0.50) | ACHETSHRALDH1A1CA1CA2 | |
| SCHEMBL18425305 | 0.83 | TSHR (0.50) | ACHETSHRALDH1A1CA1CA2 | |
| SCHEMBL138533 | 0.83 | TSHR (0.50) | ACHETSHRALDH1A1CA1CA2 | |
| SCHEMBL2502467 | 0.83 | TSHR (0.50) | ACHETSHRALDH1A1CA1CA2 | |
| Bromide SCHEMBL3688252 | 0.83 | TSHR (0.50) | ACHETSHRALDH1A1CA1CA2 | |
| SCHEMBL199961 | 0.83 | TSHR (0.50) | ACHETSHRALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105218790-B | A kind of preparation method of poly- (the 3 acyl group substituted thiophene) derivative of high regularity headtotail | 天津理工大学 | 2018-02-06 | — | — | CN | claimed |
| CN-105218790-A | The preparation method of poly-(the 3-acyl substituted thiophene) derivative of a kind of high regularity head-to-tail | UNIV TIANJIN TECHNOLOGY | 2016-01-06 | — | — | CN | claimed |
| EP-1358192-B1 | PROCESS FOR THE PRODUCTION OF MONOALKYLTIN TRIHALIDES | ATOFINA VLISSINGEN B V (NL) | 2006-04-26 | — | — | EP | claimed |
| US-6768017-B2 | Process for the production of monoalkyltin trihalides | ATOFINA VLISSINGEN B.V. (NL) | 2004-07-27 | — | — | US | claimed |
| US-20040077891-A1 | Process for the production of monoalkyltin thihalides | ATOFINA VLISSINGEN B.V. (NL) | 2004-04-22 | — | — | US | claimed |
| EP-1358192-A1 | PROCESS FOR THE PRODUCTION OF MONOALKYLTIN TRIHALIDES | Atofina Vlissingen B.V. (NL) | 2003-11-05 | — | — | EP | claimed |
| WO-2002057277-A1 | PROCESS FOR THE PRODUCTION OF MONOALKYLTIN TRIHALIDES | ATOFINA VLISSINGEN B.V. (NL) | 2002-07-25 | — | — | WO | claimed |
| EP-1225177-A1 | Process for the production of monoalkyltin trihalides | Atofina Vlissingen B.V. (NL) | 2002-07-24 | — | — | EP | claimed |
| CN-105451737-B | Medical composition and its use and described pharmaceutical composition are used for the application process practised contraception on demand | 拜耳医药股份有限公司 | 2018-04-10 | — | — | CN | disclosed |
| CN-105218790-B | A kind of preparation method of poly- (the 3 acyl group substituted thiophene) derivative of high regularity headtotail | 天津理工大学 | 2018-02-06 | — | — | CN | disclosed |
| CN-104744491-B | Benzo oxazepine * PI3K inhibitor compounds and application method | 霍夫曼-拉罗奇有限公司 | 2017-07-11 | — | — | CN | disclosed |
| CN-106565940-A | Method for preparing high-regularity head-to-tail polythiophene derivatives | 天津理工大学 | 2017-04-19 | — | — | CN | disclosed |
| CN-106232589-A | Tetracarboxylic dianhydride, polyamic acid, polyimides and those manufacture method and polyamic acid solution | 捷客斯能源株式会社 | 2016-12-14 | — | — | CN | disclosed |
| CN-105814054-A | Fused imidazole and pyrazole derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-07-27 | — | — | CN | disclosed |
| WO-2000037022-A2 | COMBINATION THERAPY FOR THE TREATMENT OF SEPSIS | ELI LILLY AND COMPANY (US) | 2000-06-29 | — | — | WO | disclosed |
| EP-1011670-A1 | METHOD FOR TREATMENT OF NON-RHEUMATOID ATHRITIS | ELI LILLY AND COMPANY (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-1999025340-A1 | TREATMENT FOR ALZHEIMER'S DISEASE | ELI LILLY AND COMPANY (US) | 1999-05-27 | — | — | WO | disclosed |
| WO-1999021935-A1 | LIGHT-EMITTING DENDRIMERS AND DEVICES | ISIS INNOVATION LIMITED (GB) | 1999-05-06 | — | — | WO | disclosed |
| WO-1999009978-A1 | METHOD FOR TREATMENT OF NON-RHEUMATOID ATHRITIS | ELI LILLY AND COMPANY (US) | 1999-03-04 | — | — | WO | disclosed |
| US-5698755-A | Process for preparing aromatic olefins using palladacycle catalysis | HOECHST AG (DE) | 1997-12-16 | — | — | US | disclosed |