SCHEMBL3883387

SCHEMBL3883387

Cc1cc(-c2ccccc2F)c(P(=O)(O)O)c(-c2ccccc2F)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 1/20 0.39
MAPT P10636 3/20 0.38
NPSR1 Q6W5P4 2/20 0.38
POLB P06746 1/20 0.38
HPGD P15428 1/20 0.38
CASP3 P42574 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
CA12 O43570 1/20 0.38
CA9 Q16790 1/20 0.38
PGK1 P00558 1/20 0.37
PGK2 P07205 1/20 0.37
PPIA P62937 1/20 0.36
DHODH Q02127 2/20 0.35
ELANE P08246 1/20 0.35
ALDH1A1 P00352 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MBNL1 Q9NR56 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3893674 0.81 PTPRC (0.41) GRM2MAPTNPSR1CA12CA9
SCHEMBL779346 0.79 GRM2 (0.39) GRM2MAPTNPSR1POLBHPGD
SCHEMBL3883447 0.76 BRD4 (0.37) MAPTHPGDPGK1PGK2ELANE
SCHEMBL3893677 0.76 ELANE (0.35) GRM2MAPTNPSR1CASP3SMN1; SMN2
SCHEMBL3896492 0.76 HDAC7 (0.41) MAPTHPGDSMN1; SMN2CA12CA9
SCHEMBL3887561 0.72 HDAC7 (0.47) MAPTPOLBHPGDSMN1; SMN2ALDH1A1
SCHEMBL3636762 0.71 ELANE (0.48) GRM2MAPTNPSR1POLBHPGD
SCHEMBL11418617 0.71 LMNA (0.43) HPGDCA12CA9PGK1PGK2
SCHEMBL776970 0.69 MAPT (0.38) MAPTNPSR1HPGDCA12CA9
SCHEMBL25400238 0.69 MAPT (0.61) GRM2MAPTNPSR1POLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090325065-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2009-12-31 US disclosed