Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 12/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3883684 | 1.00 | HTR4 (0.51) | HTR4TMEM97SIGMAR1HTR3A | |
| SCHEMBL3768023 | 1.00 | HTR4 (0.51) | HTR4TMEM97SIGMAR1HTR3A | |
| SCHEMBL3883676 | 1.00 | HTR4 (0.51) | HTR4TMEM97SIGMAR1HTR3A | |
| SCHEMBL3768025 | 1.00 | HTR4 (0.51) | HTR4TMEM97SIGMAR1HTR3A | |
| SCHEMBL3767664 | 0.92 | HTR4 (0.52) | HTR4TMEM97SIGMAR1HTR3A | |
| SCHEMBL3767662 | 0.92 | HTR4 (0.52) | HTR4TMEM97SIGMAR1HTR3A | |
| SCHEMBL3839512 | 0.90 | HTR4 (0.48) | HTR4TMEM97SIGMAR1HTR3A | |
| SCHEMBL3839507 | 0.90 | HTR4 (0.48) | HTR4TMEM97SIGMAR1HTR3A | |
| SCHEMBL3773752 | 0.90 | HTR4 (0.47) | HTR4TMEM97SIGMAR1HTR3A | |
| SCHEMBL3839509 | 0.90 | HTR4 (0.48) | HTR4TMEM97SIGMAR1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960396-B1 | CARBAMATE COMPOUNDS AS 5-HT4 RECEPTOR AGONISTS | THERAVANCE INC (US) | 2009-11-11 | — | — | EP | claimed |