Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4454062 | 0.78 | CYP2C19 (0.33) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| SCHEMBL11790119 | 0.77 | TP53 (0.32) | — | |
| SCHEMBL841332 | 0.71 | — | — | |
| SCHEMBL27280076 | 0.70 | FDPS (0.32) | — | |
| SCHEMBL22856852 | 0.69 | — | — | |
| SCHEMBL12290757 | 0.68 | — | — | |
| SCHEMBL7054514 | 0.66 | — | — | |
| SCHEMBL30153329 | 0.66 | — | — | |
| Diethylamine SCHEMBL27835702 | 0.64 | TP53 (0.33) | — | |
| SCHEMBL30363145 | 0.64 | CYP2C19 (0.36) | CYP2C19MEN1GLAKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3807250-A1 | DISUBSTITUTED 5(3)-PYRAZOLE CARBOXYLATES AND A PROCESS FOR THEIR PREPARATION FROM ENOLATES AND FLUOROALKYLAMINOREAGENTS (FAR) REAGENTS | Bayer Aktiengesellschaft (DE) | 2021-04-21 | — | — | EP | claimed |
| WO-2019243179-A1 | DISUBSTITUTED 5(3)-PYRAZOLE CARBOXYLATES AND A PROCESS FOR THEIR PREPARATION FROM ENOLATES AND FLUOROALKYLAMINOREAGENTS (FAR) REAGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2019-12-26 | — | — | WO | claimed |
| EP-3068769-A1 | PROCESS FOR PREPARING 3,5-BIS(HALOALKYL)PYRAZOLE DERIVATIVES FROM ALPHA, APLHA-DIHALOAMINES | Bayer CropScience Aktiengesellschaft (DE) | 2016-09-21 | — | — | EP | claimed |
| WO-2015067802-A1 | PROCESS FOR PREPARING 3,5-BIS(HALOALKYL)PYRAZOLE DERIVATIVES FROM α,α-DIHALOAMINES | BAYER CROPSCIENCE AG (DE) | 2015-05-14 | — | — | WO | claimed |
| EP-2114855-A2 | METHOD FOR PRODUCING DIHALO ACETOACETIC ALKYL ESTERS | Bayer CropScience Aktiengesellschaft (DE) | 2009-11-11 | — | — | EP | claimed |
| WO-2008092583-A2 | METHOD FOR PRODUCING DIHALO ACETOACETIC ALKYL ESTERS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-08-07 | — | — | WO | claimed |
| EP-3807250-A1 | DISUBSTITUTED 5(3)-PYRAZOLE CARBOXYLATES AND A PROCESS FOR THEIR PREPARATION FROM ENOLATES AND FLUOROALKYLAMINOREAGENTS (FAR) REAGENTS | Bayer Aktiengesellschaft (DE) | 2021-04-21 | — | — | EP | disclosed |
| WO-2019243179-A1 | DISUBSTITUTED 5(3)-PYRAZOLE CARBOXYLATES AND A PROCESS FOR THEIR PREPARATION FROM ENOLATES AND FLUOROALKYLAMINOREAGENTS (FAR) REAGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2019-12-26 | — | — | WO | disclosed |
| EP-3122727-A1 | PROCESS FOR PREPARING 3,5-BIS(HALOALKYL)PYRAZOLE DERIVATIVES FROM , -DIHALOAMINES AND KETIMINES | Bayer CropScience Aktiengesellschaft (DE) | 2017-02-01 | — | — | EP | disclosed |
| EP-3068769-A1 | PROCESS FOR PREPARING 3,5-BIS(HALOALKYL)PYRAZOLE DERIVATIVES FROM ALPHA, APLHA-DIHALOAMINES | Bayer CropScience Aktiengesellschaft (DE) | 2016-09-21 | — | — | EP | disclosed |
| EP-2999694-A1 | PROCESS FOR PREPARING 3,5-BIS(FLUOROALKYL)PYRAZOLE DERIVATIVES FROM ALPHA,ALPHA -DIHALOAMINES | Bayer CropScience Aktiengesellschaft (DE) | 2016-03-30 | — | — | EP | disclosed |
| WO-2015144578-A1 | PROCESS FOR PREPARING 3,5-BIS(HALOALKYL)PYRAZOLE DERIVATIVES FROM α,α-DIHALOAMINES AND KETIMINES | BAYER CROPSCIENCE AG (DE) | 2015-10-01 | — | — | WO | disclosed |
| EP-2890682-A1 | PROCEDURE FOR THE DECARBOXYLATION OF 3,5-BIS(HALOALKYL)-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2015-07-08 | — | — | EP | disclosed |
| WO-2014033164-A1 | PROCEDURE FOR THE DECARBOXYLATION OF 3,5-BIS(HALOALKYL)-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2014-03-06 | — | — | WO | disclosed |
| WO-2013113829-A1 | METHOD FOR PRODUCING 3,5-BIS(FLUOROALKYL)-PYRAZOL-4-CARBOXYLIC ACID DERIVATIVES AND 3,5-BIS(FLUOROALKYL)-PYRAZOLES | BAYER CROPSCIENCE AG (DE) | 2013-08-08 | — | — | WO | disclosed |
| CN-101151232-B | Process for production of fluorocompounds | TOSOH F TECH INC | 2011-07-13 | — | — | CN | disclosed |
| EP-2057126-A2 | PROCESS FOR PREPARING 3-DIHALOMETHYLPYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2009-05-13 | — | — | EP | disclosed |
| EP-2012799-A2 | METABOLICALLY STABLE ALKOXYALKYL ESTERS OF ANTIVIRAL OR ANTIPROLIFERATIVE PHOSPHONATES, NUCLEOSIDE PHOSPHONATES AND NUCLEOSIDE PHOSPHATES | Chimerix, Inc. (US) | 2009-01-14 | — | — | EP | disclosed |
| WO-2008022777-A2 | PROCESS FOR PREPARING 3-DIHALOMETHYLPYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-02-28 | — | — | WO | disclosed |
| WO-2007130783-A2 | METABOLICALLY STABLE ALKOXYALKYL ESTERS OF ANTIVIRAL OR ANTIPROLIFERATIVE PHOSPHONATES, NUCLEOSIDE PHOSPHONATES AND NUCLEOSIDE PHOSPHATES | CHIMERIX, INC. (US) | 2007-11-15 | — | — | WO | disclosed |