SCHEMBL3883808

SCHEMBL3883808

CCn1ccc2cc(-c3cc(CCC(=O)O)ccc3OCc3ccc(F)cc3)ccc21

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 11/20 0.49
FFAR1 O14842 8/20 0.48
TP53 P04637 4/20 0.47
MDM2 Q00987 4/20 0.47
PPARG P37231 1/20 0.45
NR1H2 P55055 1/20 0.45
PPARD Q03181 1/20 0.45
PPARA Q07869 1/20 0.45
NR1H3 Q13133 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3884482 0.91 PPARD (0.52) FFAR4FFAR1PPARGNR1H2PPARD
SCHEMBL3882479 0.89 FFAR4 (0.51) FFAR4FFAR1TP53MDM2
SCHEMBL3890117 0.84 FFAR4 (0.57) FFAR4FFAR1
SCHEMBL3884123 0.84 TP53 (0.49) FFAR4FFAR1TP53MDM2
SCHEMBL3889278 0.83 PPARG (0.45) FFAR4FFAR1TP53MDM2PPARG
SCHEMBL3881653 0.82 THRA (0.43) FFAR4FFAR1TP53MDM2PPARG
SCHEMBL3882096 0.81 FFAR4 (0.49) FFAR4FFAR1TP53MDM2
SCHEMBL3886504 0.81 FFAR4 (0.48) FFAR4FFAR1PPARGNR1H2PPARD
SCHEMBL3882007 0.80 FFAR4 (0.59) FFAR4FFAR1TP53MDM2
SCHEMBL3883490 0.80 FFAR4 (0.44) FFAR4FFAR1PPARGNR1H2PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1477472-B1 SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF ASAHI KASEI PHARMA CORP (JP) 2009-01-14 EP claimed
US-6867320-B2 Substituted phenylalkanoic acid derivatives and use thereof ASAHI KASEI PHARMA CORPORATION (JP) 2005-03-15 US claimed
EP-1477472-A1 SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF Asahi Kasei Pharma Corporation (JP) 2004-11-17 EP claimed
US-20040044258-A1 Substituted phenylalkanoic acid derivatives and use thereof ASAHI KASEI PHARMA CORPORATION (JP) 2004-03-04 US claimed
EP-1477472-B1 SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF ASAHI KASEI PHARMA CORP (JP) 2009-01-14 EP disclosed
US-6867320-B2 Substituted phenylalkanoic acid derivatives and use thereof ASAHI KASEI PHARMA CORPORATION (JP) 2005-03-15 US disclosed
EP-1477472-A1 SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF Asahi Kasei Pharma Corporation (JP) 2004-11-17 EP disclosed
US-20040044258-A1 Substituted phenylalkanoic acid derivatives and use thereof ASAHI KASEI PHARMA CORPORATION (JP) 2004-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040044258-A1 Substituted phenylalkanoic acid derivatives and use thereof PTGER1, CYSLTR1, PTGS1 FFAR4 115/4885FFAR1 13/4885TP53 4018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.