SCHEMBL3883909

SCHEMBL3883909

CCCCOc1ccc(CC(C)C(=O)O)cc1-c1ccc2ccccc2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 8/20 0.45
PTGES O14684 2/20 0.45
ALOX5 P09917 2/20 0.45
PPARA Q07869 7/20 0.45
PPARD Q03181 5/20 0.45
PTPN11 Q06124 1/20 0.43
CNR2 P34972 1/20 0.43
PLA2G10 O15496 3/20 0.43
PLA2G2A P14555 3/20 0.43
PTGER1 P34995 1/20 0.43
PTGER4 P35408 1/20 0.43
PTGER3 P43115 1/20 0.43
PTGER2 P43116 1/20 0.43
PLA2G1B P04054 1/20 0.43
PLA2G5 P39877 1/20 0.43
PLA2G2C Q5R387 1/20 0.43
PLA2G12B Q9BX93 1/20 0.43
PLA2G12A Q9BZM1 1/20 0.43
PLA2G2F Q9BZM2 1/20 0.43
PLA2G3 Q9NZ20 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3894526 0.89 PPARG (0.47) PPARGPTGESALOX5PPARAPPARD
SCHEMBL3891271 0.87 PTGER1 (0.57) PPARGALOX5PPARAPLA2G10PLA2G2A
SCHEMBL3882422 0.87 PPARA (0.49) PPARGPTGESALOX5PPARAPPARD
SCHEMBL3881338 0.86 PTPN1 (0.46) PPARGPPARAPPARDPLA2G10PLA2G2A
SCHEMBL3882300 0.85 PTGS2 (0.45) PPARGPTGESALOX5PPARAPPARD
SCHEMBL3887234 0.84 FFAR4 (0.52) PPARGPPARAPPARDPLA2G10PLA2G2A
SCHEMBL3883021 0.84 S1PR5 (0.46) PPARGPPARAPPARDPLA2G10PLA2G2A
SCHEMBL3884628 0.84 PPARG (0.48) PPARGPTGESALOX5PPARAPPARD
SCHEMBL3883200 0.84 PPARG (0.44) PPARGPTGESALOX5PPARAPPARD
SCHEMBL3884272 0.83 PPARA (0.44) PPARGPTGESALOX5PPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1477472-B1 SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF ASAHI KASEI PHARMA CORP (JP) 2009-01-14 EP claimed