SCHEMBL3884293

SCHEMBL3884293

CC(C)c1cc(C2(c3cc(C(C)C)c(Oc4ccc(N)cc4)c(C(C)C)c3)c3ccccc3-c3ccccc32)cc(C(C)C)c1Oc1ccc(N)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.50
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
MAPT P10636 4/20 0.50
LMNA P02545 2/20 0.50
KDM4E B2RXH2 1/20 0.50
OPRK1 P41145 1/20 0.50
KDM1A O60341 1/20 0.38
MAOA P21397 1/20 0.37
NCOA1 Q15788 1/20 0.36
NCOA3 Q9Y6Q9 1/20 0.36
ALDH1A1 P00352 6/20 0.35
MITF O75030 1/20 0.35
GAA P10253 1/20 0.35
GFER P55789 1/20 0.35
NLRP1 Q9C000 1/20 0.35
NOD2 Q9HC29 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
NLRP3 Q96P20 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29418509 0.85 KDM4E (0.44) SMN1; SMN2MEN1KMT2AMAPTLMNA
SCHEMBL3875126 0.85 KDM4E (0.44) SMN1; SMN2MEN1KMT2AMAPTLMNA
SCHEMBL2443500 0.85 SMN1; SMN2 (0.51) SMN1; SMN2MEN1KMT2AMAPTLMNA
SCHEMBL3874336 0.83 LMNA (0.42) SMN1; SMN2MEN1KMT2AMAPTLMNA
SCHEMBL2448298 0.82 SMN1; SMN2 (0.54) SMN1; SMN2MEN1KMT2AMAPTLMNA
SCHEMBL30295994 0.80 SMN1; SMN2 (0.51) SMN1; SMN2MEN1KMT2AMAPTLMNA
SCHEMBL3874551 0.80 KDM4E (0.40) SMN1; SMN2MEN1KMT2AMAPTLMNA
SCHEMBL3872560 0.80 KDM4E (0.43) SMN1; SMN2MEN1KMT2AMAPTLMNA
SCHEMBL2442533 0.80 MEN1 (0.51) SMN1; SMN2MEN1KMT2AMAPTLMNA
SCHEMBL2442274 0.79 MAPT (0.50) SMN1; SMN2MEN1KMT2AMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2128193-B1 POROUS POLYIMIDE IBIDEN CO LTD (JP) 2013-06-19 EP disclosed
EP-2128193-A1 POROUS POLYIMIDE Ibiden Co., Ltd. (JP) 2009-12-02 EP disclosed