Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL28891380 | 0.94 | — | — | |
| Alcohol SCHEMBL2703737 | 0.94 | — | — | |
| Alcohol SCHEMBL7688108 | 0.89 | — | — | |
| Alcohol SCHEMBL27658960 | 0.89 | — | — | |
| Alcohol SCHEMBL10888428 | 0.88 | — | — | |
| Alcohol SCHEMBL377849 | 0.88 | ALDH1A1 (0.86) | TSHRALDH1A1TDP1SMN1; SMN2 | |
| Alcohol SCHEMBL1740203 | 0.88 | — | — | |
| Alcohol SCHEMBL18941 | 0.88 | — | — | |
| Alcohol SCHEMBL819132 | 0.88 | — | — | |
| Alcohol SCHEMBL6259193 | 0.88 | ALDH1A1 (0.86) | TSHRALDH1A1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488908-B2 | Liquid metal switch employing a switching material containing gallium | AGILENT TECHNOLOGIES, INC. (US) | 2009-02-10 | — | — | US | claimed |
| EP-1777719-B1 | Liquid metal switch employing a switching material containing gallium | AGILENT TECHNOLOGIES INC (US) | 2009-01-14 | — | — | EP | claimed |
| US-20070089975-A1 | Liquid metal switch employing a switching material containing gallium | AGILENT TECHNOLOGIES, INC. | 2007-04-26 | — | — | US | claimed |
| EP-1777719-A1 | Liquid metal switch employing a switching material containing gallium | Agilent Technologies, Inc. (US) | 2007-04-25 | — | — | EP | claimed |
| US-7488908-B2 | Liquid metal switch employing a switching material containing gallium | AGILENT TECHNOLOGIES, INC. (US) | 2009-02-10 | — | — | US | disclosed |
| EP-1777719-B1 | Liquid metal switch employing a switching material containing gallium | AGILENT TECHNOLOGIES INC (US) | 2009-01-14 | — | — | EP | disclosed |
| US-20070089975-A1 | Liquid metal switch employing a switching material containing gallium | AGILENT TECHNOLOGIES, INC. | 2007-04-26 | — | — | US | disclosed |
| EP-1777719-A1 | Liquid metal switch employing a switching material containing gallium | Agilent Technologies, Inc. (US) | 2007-04-25 | — | — | EP | disclosed |
| CN-1953116-A | Liquid metal switch employing a switching material containing gallium | AGILENT TECHNOLOGIES INC (US) | 2007-04-25 | — | — | CN | disclosed |