SCHEMBL3884563

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3887066	0.90	ROCK1 (0.71)	ROCK1RPS6KA1RPS6KB1ROCK2TP53
	SCHEMBL3884120	0.90	GPBAR1 (0.49)	ROCK1RPS6KA1RPS6KB1ROCK2TP53
	SCHEMBL3896684	0.89	ROCK1 (0.57)	ROCK1RPS6KA1RPS6KB1ROCK2TP53
	SCHEMBL3886366	0.84	ROCK1 (0.81)	ROCK1RPS6KA1RPS6KB1ROCK2TP53
	SCHEMBL3886638	0.83	ROCK1 (0.58)	ROCK1RPS6KA1RPS6KB1ROCK2TP53
	SCHEMBL3886646	0.80	ROCK1 (0.59)	ROCK1RPS6KA1RPS6KB1ROCK2TP53
	SCHEMBL3886340	0.79	ROCK1 (0.57)	ROCK1RPS6KA1RPS6KB1ROCK2TP53
	SCHEMBL3885671	0.78	ROCK1 (0.50)	ROCK1RPS6KA1RPS6KB1ROCK2TP53
	SCHEMBL3885704	0.78	ROCK1 (0.56)	ROCK1RPS6KA1RPS6KB1ROCK2TP53
	SCHEMBL3887118	0.77	ROCK1 (0.73)	ROCK1RPS6KA1RPS6KB1ROCK2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.