Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL3884716

Cn1c(=O)n(Cc2ccccc2)c2c(N3CCNCC3)nc(Cl)nc21.O=C(O)C(F)(F)F

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 8/20 0.56
L3MBTL1 Q9Y468 1/20 0.46
P2RX3 P56373 2/20 0.46
ALDH1A1 P00352 4/20 0.44
TSHR P16473 3/20 0.44
NPSR1 Q6W5P4 3/20 0.44
LMNA P02545 1/20 0.44
TP53 P04637 1/20 0.43
THRB P10828 1/20 0.43
FAP Q12884 1/20 0.42
MAPK1 P28482 2/20 0.42
RECQL P46063 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
HTR6 P50406 1/20 0.41
ALOX15 P16050 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13866871 0.92 DPP4 (0.64) DPP4L3MBTL1P2RX3ALDH1A1TSHR
Trifluoroacetic Acid SCHEMBL3885741 0.86 DPP4 (0.53) DPP4P2RX3FAPHTR6
Trifluoroacetic Acid SCHEMBL3875965 0.86 DPP4 (0.52) DPP4L3MBTL1ALDH1A1TSHRNPSR1
Trifluoroacetic Acid SCHEMBL3872986 0.84 DPP4 (0.41) DPP4L3MBTL1ALDH1A1TSHRLMNA
Trifluoroacetic Acid SCHEMBL3872990 0.84 DPP4 (0.41) DPP4L3MBTL1ALDH1A1TSHRLMNA
Trifluoroacetic Acid SCHEMBL3886671 0.84 DPP4 (0.54) DPP4ALDH1A1LMNAMAPK1
Trifluoroacetic Acid SCHEMBL3879690 0.84 DPP4 (0.52) DPP4L3MBTL1FAP
Trifluoroacetic Acid SCHEMBL3879362 0.84 DPP4 (0.42) DPP4L3MBTL1ALDH1A1LMNA
Trifluoroacetic Acid SCHEMBL3876004 0.83 DPP4 (0.43) DPP4L3MBTL1LMNAFAP
Trifluoroacetic Acid SCHEMBL3887064 0.83 DPP4 (0.50) DPP4P2RX3ALDH1A1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7524847-B2 Fused 1,3-dihydro-imidazole ring compounds EISAI R&D MANAGEMENT CO., LTD. (JP) 2009-04-28 US disclosed
EP-1568699-A1 1,3-DIHYDROIMIDAZOLE FUSED-RING COMPOUND Eisai Co., Ltd. (JP) 2005-08-31 EP disclosed