Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | FAP | Q12884 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3884716 | 0.92 | DPP4 (0.56) | DPP4L3MBTL1TP53THRBALDH1A1 | |
| SCHEMBL13876140 | 0.86 | DPP4 (0.52) | DPP4HTR6P2RX3 | |
| SCHEMBL13875834 | 0.84 | DPP4 (0.46) | DPP4L3MBTL1ALDH1A1TSHRFAP | |
| SCHEMBL13866891 | 0.84 | DPP4 (0.60) | DPP4FAPHTR6P2RX3 | |
| SCHEMBL13867033 | 0.83 | DPP4 (0.59) | DPP4L3MBTL1TP53THRBALDH1A1 | |
| SCHEMBL13875675 | 0.83 | DPP4 (0.45) | DPP4L3MBTL1TP53ALDH1A1RECQL | |
| SCHEMBL13876136 | 0.82 | DPP4 (0.48) | DPP4TP53ALDH1A1MAPK1HSD17B10 | |
| SCHEMBL13866887 | 0.80 | DPP4 (0.56) | DPP4TP53ALDH1A1MAPK1FAP | |
| SCHEMBL13876111 | 0.80 | DPP4 (0.44) | DPP4L3MBTL1TP53ALDH1A1MAPK1 | |
| SCHEMBL13866842 | 0.80 | DPP4 (0.61) | DPP4L3MBTL1FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |