Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.38 |
| ▸ | PI4KA | P42356 | 6/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 6/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3888367 | 0.91 | PDE4B (0.44) | PPARGNPC1RAB9ALMNAPPARD | |
| SCHEMBL3884291 | 0.89 | CYP1A2 (0.40) | CYP1A2PIK3CAPI4KAPI4KBPIK3CD | |
| SCHEMBL3894944 | 0.89 | PPARG (0.39) | PPARGNPC1RAB9ALMNAPPARD | |
| SCHEMBL3882487 | 0.89 | ABL1 (0.42) | PPARGABL1 | |
| SCHEMBL3891599 | 0.88 | CYP1A2 (0.41) | PPARGCYP1A2PIK3CAPI4KAPI4KB | |
| SCHEMBL3882082 | 0.88 | CYP1A2 (0.40) | PPARGCYP1A2PIK3CAPI4KAPI4KB | |
| SCHEMBL3882136 | 0.86 | PPARG (0.41) | PPARGPPARDPPARAPLA2G10PLA2G2A | |
| SCHEMBL3884753 | 0.85 | PPARD (0.43) | PPARGCYP1A2PIK3CAPI4KAPI4KB | |
| SCHEMBL3882781 | 0.84 | S1PR1 (0.46) | CYP1A2PIK3CAPI4KAPI4KBPIK3CD | |
| SCHEMBL3884531 | 0.83 | MAP4K4 (0.36) | PPARGCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |