Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | XDH | P47989 | 3/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3884992 | 0.91 | PPARG (0.40) | NPC1RAB9APPARGPPARAPPARD | |
| SCHEMBL3882487 | 0.90 | ABL1 (0.42) | PDE4BPPARGABL1 | |
| SCHEMBL3894944 | 0.90 | PPARG (0.39) | PDE4BNPC1RAB9APPARGXDH | |
| SCHEMBL3882136 | 0.86 | PPARG (0.41) | PDE4BPPARGXDHPPARAPPARD | |
| SCHEMBL3884679 | 0.84 | S1PR1 (0.49) | PDE4BNPC1RAB9AXDHCCNE1 | |
| SCHEMBL3887136 | 0.83 | PDE4B (0.40) | PDE4BNPC1RAB9AXDHKEAP1 | |
| SCHEMBL3885523 | 0.82 | NPC1 (0.43) | PDE4BNPC1RAB9AXDHCCNE1 | |
| SCHEMBL3884528 | 0.81 | PPARG (0.46) | PPARGPPARAPPARDKEAP1NFE2L2 | |
| SCHEMBL3884648 | 0.80 | PPARG (0.41) | PPARGPPARAPPARDKEAP1NFE2L2 | |
| SCHEMBL3884291 | 0.80 | CYP1A2 (0.40) | NPC1RAB9AXDHLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |