Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.61 |
| ▸ | MAPT | P10636 | 12/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | ALPL | P05186 | 1/20 | 0.58 |
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | ALPG | P10696 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 4/20 | 0.47 |
| ▸ | SNCA | P37840 | 4/20 | 0.47 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3885759 | 1.00 | MEN1 (0.61) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL14041425 | 0.87 | KMT2A (0.60) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL4748813 | 0.87 | KMT2A (0.60) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL10035978 | 0.84 | KMT2A (0.76) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL418891 | 0.80 | MEN1 (0.60) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL445970 | 0.80 | MEN1 (0.60) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL12589929 | 0.77 | KMT2A (0.65) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL420801 | 0.76 | KMT2A (1.00) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL444132 | 0.76 | KMT2A (1.00) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL444133 | 0.76 | KMT2A (1.00) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563554-B2 | Electrophotographic toner | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2009-07-21 | — | — | US | disclosed |
| US-7534273-B2 | Cationic pyrazolone dyes, method for production thereof and coloring agents for keratin fibers containing said compounds | WELLA AG (DE) | 2009-05-19 | — | — | US | disclosed |
| US-7470495-B2 | Electrophotographic toner and image forming method | KONICA MINOLTA HOLDINGS, INC. (JP) | 2008-12-30 | — | — | US | disclosed |
| US-20080263787-A1 | Cationic Pyrazolone Dyes, Method for Production Thereof and Coloring Agents for Keratin Fibers Containing Said Compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2008-10-30 | — | — | US | disclosed |
| US-7374278-B2 | Water-based ink containing colored microparticle dispersion | KONICA MINOLTA HOLDINGS, INC. (JP) | 2008-05-20 | — | — | US | disclosed |
| US-20070099106-A1 | ELECTROPHOTOGRAPHIC TONER | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2007-05-03 | — | — | US | disclosed |
| EP-1771517-A1 | CATIONIC PYRAZOLONE DYES METHOD FOR PRODUCTION THEREOF AND COLOURING AGENTS FOR KERATIN FIBRES CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006012934-A1 | CATIONIC PYRAZOLONE DYES METHOD FOR PRODUCTION THEREOF AND COLOURING AGENTS FOR KERATIN FIBRES CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2006-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080263787-A1 | Cationic Pyrazolone Dyes, Method for Production Thereof and Coloring Agents for Keratin Fibers Containing Said Compounds | KRT18, KLK5, IK | MEN1 4265/4885KMT2A 3682/4885MAPT 1821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.