Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 14/20 | 0.60 |
| ▸ | MEN1 | O00255 | 12/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.60 |
| ▸ | MMP2 | P08253 | 1/20 | 0.60 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.60 |
| ▸ | MMP14 | P50281 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14041425 | 1.00 | KMT2A (0.60) | KMT2AMEN1MAPTL3MBTL1NPSR1 | |
| SCHEMBL4746370 | 0.88 | KMT2A (0.62) | KMT2AMEN1MAPTL3MBTL1NPSR1 | |
| SCHEMBL4746375 | 0.88 | KMT2A (0.62) | KMT2AMEN1MAPTL3MBTL1NPSR1 | |
| SCHEMBL3885765 | 0.87 | MEN1 (0.61) | KMT2AMEN1MAPTL3MBTL1NPSR1 | |
| SCHEMBL3885759 | 0.87 | MEN1 (0.61) | KMT2AMEN1MAPTL3MBTL1NPSR1 | |
| SCHEMBL4749150 | 0.86 | ALDH1A1 (0.46) | KMT2AMEN1MAPTL3MBTL1NPSR1 | |
| SCHEMBL4749377 | 0.86 | ALDH1A1 (0.46) | KMT2AMEN1MAPTL3MBTL1NPSR1 | |
| SCHEMBL12924705 | 0.85 | KMT2A (0.67) | KMT2AMEN1MAPTL3MBTL1NPSR1 | |
| SCHEMBL14198801 | 0.85 | KMT2A (0.67) | KMT2AMEN1MAPTL3MBTL1NPSR1 | |
| SCHEMBL4745704 | 0.80 | KMT2A (0.58) | KMT2AMEN1MAPTL3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008121861-A2 | PYRAZOLE AND PYRROLE COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2008-10-09 | — | — | WO | disclosed |