Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | HTT | P42858 | 4/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3616209 | 0.89 | THRB (0.65) | THRBMAPTHTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL1644345 | 0.88 | THRB (0.59) | THRBMAPTHTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL27836733 | 0.88 | MAPT (0.63) | THRBMAPTHTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL3885112 | 0.84 | THRB (0.67) | THRBMAPTHTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL1647287 | 0.84 | THRB (0.70) | THRBMAPTHTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL1646719 | 0.79 | THRB (0.63) | THRBMAPTHTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL1645186 | 0.78 | MAPT (0.78) | THRBMAPTHTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL1644582 | 0.78 | THRB (0.64) | THRBMAPTHTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL1645686 | 0.78 | THRB (0.74) | THRBMAPTHTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL1645318 | 0.77 | THRB (1.00) | THRBMAPTHTTL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888063-B1 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-01-14 | — | — | EP | claimed |