SCHEMBL388653

SCHEMBL388653

C=C[Sn](C=C)(CCCC)CCCC

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.33
THRB P10828 1/20 0.32
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15018875 0.89 TSHR (0.46) TSHRALDH1A1LMNATHRB
SCHEMBL3096180 0.77 TSHR (0.41) TSHRALDH1A1LMNATHRBHPGD
SCHEMBL41245 0.77 TSHR (0.41) TSHRALDH1A1LMNATHRBHPGD
SCHEMBL1566900 0.74 TSHR (0.39) TSHRALDH1A1LMNATHRB
SCHEMBL11057751 0.74 TSHR (0.39) TSHRALDH1A1LMNATHRB
SCHEMBL1028079 0.72 TSHR (0.38) TSHRALDH1A1LMNA
SCHEMBL1031853 0.72
SCHEMBL1029876 0.72 TSHR (0.38) TSHRALDH1A1LMNA
SCHEMBL1027136 0.72 TSHR (0.38) TSHRALDH1A1LMNA
SCHEMBL29180735 0.71 TSHR (0.41) TSHRALDH1A1LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124273-B2 Nonaqueous electrolyte solution and lithium secondary battery using same UBE INDUSTRIES, LTD. (JP) 2012-02-28 US claimed
US-8101697-B2 Multi-functionalized high-trans elastomeric polymers BRIDGESTONE CORPORATION (JP) 2012-01-24 US claimed
US-20090280404-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY USING SAME UBE INDUSTRIES LTD (JP) 2009-11-12 US claimed
US-20060173145-A1 Multi-functionalized high-trans elastomeric polymers BRIDGESTONE CORPORATION (JP) 2006-08-03 US claimed
US-6627720-B2 Monoethylenically unsaturated monomers are polymerized with at least one multiethylenically unsaturated monomer at high temperatures by free radical polymerization in a continuous reactor, without formation of highly crosslinked gels JOHNSON POLYMER, LLC 2003-09-30 US claimed
US-20020010258-A1 Silica reinforced rubber composition and article with component thereof, including tires GOODYEAR TIRE & RUBBER COMPANY, THE 2002-01-24 US claimed
EP-1148091-A2 Silica reinforced rubber composition and article with component thereof, including tires THE GOODYEAR TIRE & RUBBER COMPANY (US) 2001-10-24 EP claimed
US-6265511-B1 BLEND OF DIVINYL MONOMER AND MONOETHYLENICALLY UNSATURATED MONOMER S. C. JOHNSON COMMERICAL MARKETS, INC. 2001-07-24 US claimed
US-4448940-A POLYOXAZOLINES BASED ON DINITRILES AND DIEPOXY COMPOUNDS; POLYISOCYANURATE; FLEXIBILITY; PRINTED CIRCUITS HITACHI, LTD. (JP) 1984-05-15 US claimed
US-20220332904-A1 THIOL/ISOCYANATE/(POLY-)ENE FORMULATIONS FOR ADDITIVE MANUFACTURING HENKEL AG & CO KGAA (DE) 2022-10-20 US disclosed
WO-2021043874-A1 THIOL/ISOCYANATE/(POLY-)ENE FORMULATIONS FOR ADDITIVE MANUFACTURING HENKEL AG & CO. KGAA (DE) 2021-03-11 WO disclosed
EP-3789416-A1 THIOL/ISOCYANATE/(POLY-)ENE FORMULATIONS FOR ADDITIVE MANUFACTURING Henkel AG & Co. KGaA (DE) 2021-03-10 EP disclosed
US-20130115520-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION, AND ELECTROCHEMICAL ELEMENT UTILIZING SAME UBE INDUSTRIES, LTD. (JP) 2013-05-09 US disclosed
US-20120287201-A1 PROCESS FOR PREPARING A DISPERSION OF A PARTICULATE SOLID FUJIFILM IMAGING COLORANTS LIMITED (GB) 2012-11-15 US disclosed
US-5656754-A REACTING AN ALLENYL-B-LACTAM COMPOUND WITH AN ORGANOTIN COMPOUND OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1997-08-12 US disclosed
EP-0781821-A2 Polyester powder coating composition SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1997-07-02 EP disclosed
EP-0623622-A1 PROCESS FOR PRODUCING CEPHEM COMPOUND OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1994-11-09 EP disclosed
EP-0078503-B1 THERMOSETTING RESIN COMPOSITION AND PREPOLYMER THEREOF Hitachi, Ltd. (JP) 1986-02-26 EP disclosed
US-4448940-A POLYOXAZOLINES BASED ON DINITRILES AND DIEPOXY COMPOUNDS; POLYISOCYANURATE; FLEXIBILITY; PRINTED CIRCUITS HITACHI, LTD. (JP) 1984-05-15 US disclosed
EP-0078503-A1 Thermosetting resin composition and prepolymer thereof Hitachi, Ltd. (JP) 1983-05-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060173145-A1 Multi-functionalized high-trans elastomeric polymers VCL, PUF60, JMJD6 TSHR 4359/4885ALDH1A1 3595/4885LMNA 1616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.