Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL41245 | 0.97 | TSHR (0.41) | TSHRALDH1A1LMNATHRB | |
| SCHEMBL1566900 | 0.94 | TSHR (0.39) | TSHRALDH1A1LMNATHRB | |
| SCHEMBL5457905 | 0.86 | TSHR (0.46) | TSHRALDH1A1LMNATHRB | |
| SCHEMBL29257598 | 0.80 | ALDH1A1 (0.30) | TSHRALDH1A1 | |
| SCHEMBL3930542 | 0.79 | TSHR (0.35) | TSHRALDH1A1 | |
| SCHEMBL27998291 | 0.79 | MEN1 (0.31) | TSHRTHRB | |
| Toluene SCHEMBL6586748 | 0.77 | TSHR (0.41) | TSHRLMNA | |
| SCHEMBL1027136 | 0.76 | TSHR (0.38) | TSHRALDH1A1LMNA | |
| SCHEMBL3096180 | 0.74 | TSHR (0.41) | TSHRALDH1A1LMNATHRB | |
| SCHEMBL388653 | 0.74 | TSHR (0.41) | TSHRALDH1A1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4477388-A | CHEMICAL INTERMEDIATES FOR PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1984-10-16 | — | — | US | disclosed |
| US-4233231-A | USED FOR PREPARATION OF CHEMICAL INTERMEDIATES OF PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1980-11-11 | — | — | US | disclosed |