Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13937629 | 1.00 | MAPT (0.44) | MAPTLMNANPSR1MEN1S1PR4 | |
| SCHEMBL3886732 | 1.00 | MAPT (0.44) | MAPTLMNANPSR1MEN1S1PR4 | |
| SCHEMBL3889290 | 0.92 | CA12 (0.47) | MAPTLMNANPSR1MAPK1CA12 | |
| SCHEMBL13937614 | 0.92 | CA12 (0.47) | MAPTLMNANPSR1MAPK1CA12 | |
| SCHEMBL3889286 | 0.92 | CA12 (0.47) | MAPTLMNANPSR1MAPK1CA12 | |
| SCHEMBL13937609 | 0.88 | MAPT (0.49) | MAPTLMNAMEN1KMT2ACA12 | |
| SCHEMBL3886223 | 0.88 | MAPT (0.49) | MAPTLMNAMEN1KMT2ACA12 | |
| SCHEMBL3886225 | 0.88 | MAPT (0.49) | MAPTLMNAMEN1KMT2ACA12 | |
| SCHEMBL3886761 | 0.85 | CA12 (0.42) | MAPTLMNACA12CA1CA2 | |
| SCHEMBL3887288 | 0.85 | LMNA (0.46) | MAPTLMNAMEN1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473797-B2 | Methods of 1,3-enyne preparation using copper (I) catalysts | UNIVERSITY OF MASSACHUSETTS (US) | 2009-01-06 | — | — | US | disclosed |
| EP-1745006-A4 | METHODS OF 1,3-ENYNE PREPARATION USING COPPER (I) CATALYSTS | UNIV MASSACHUSETTS (US) | 2008-04-23 | — | — | EP | disclosed |
| EP-1745006-A2 | METHODS OF 1,3-ENYNE PREPARATION USING COPPER (I) CATALYSTS | University of Massachusetts (US) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005116198-A2 | METHODS OF 1,3-ENYNE PREPARATION USING COPPER (I) CATALYSTS | UNIVERSITY OF MASSACHUSETTS (US) | 2005-12-08 | — | — | WO | disclosed |
| US-20050255575-A1 | Methods of 1,3-enyne preparation using copper (I) catalysts | NATIONAL SCIENCE FOUNDATION | 2005-11-17 | — | — | US | disclosed |