Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.77 |
| ▸ | MEN1 | O00255 | 4/20 | 0.77 |
| ▸ | MAPT | P10636 | 3/20 | 0.77 |
| ▸ | HTT | P42858 | 3/20 | 0.77 |
| ▸ | USP2 | O75604 | 3/20 | 0.77 |
| ▸ | ATM | Q13315 | 2/20 | 0.77 |
| ▸ | RGS12 | O14924 | 1/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.77 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.77 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.71 |
| ▸ | KDR | P35968 | 2/20 | 0.71 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9386920 | 1.00 | KMT2A (0.77) | KMT2AMEN1MAPTHTTUSP2 | |
| SCHEMBL1580102 | 0.95 | KMT2A (0.84) | KMT2AMEN1MAPTHTTUSP2 | |
| SCHEMBL8396375 | 0.92 | KMT2A (0.86) | KMT2AMEN1MAPTHTTUSP2 | |
| SCHEMBL8397978 | 0.92 | KMT2A (0.86) | KMT2AMEN1MAPTHTTUSP2 | |
| SCHEMBL7799818 | 0.92 | KMT2A (0.86) | KMT2AMEN1MAPTHTTUSP2 | |
| SCHEMBL1505179 | 0.91 | KMT2A (0.88) | KMT2AMEN1MAPTHTTUSP2 | |
| SCHEMBL28087595 | 0.90 | KMT2A (0.83) | KMT2AMEN1MAPTHTTUSP2 | |
| SCHEMBL7523337 | 0.88 | KMT2A (0.84) | KMT2AMEN1MAPTHTTUSP2 | |
| SCHEMBL1505189 | 0.87 | MEN1 (0.70) | KMT2AMEN1MAPTHTTUSP2 | |
| SCHEMBL29460431 | 0.87 | KMT2A (1.00) | KMT2AMEN1MAPTHTTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7528144-B2 | Molecules and methods for fluorescence microscopy | WISYS TECHNOLOGY FOUNDATION, INC. (US) | 2009-05-05 | — | — | US | disclosed |
| US-7528144-B2 | Molecules and methods for fluorescence microscopy | WISYS TECHNOLOGY FOUNDATION, INC. (US) | 2009-05-05 | — | — | US | disclosed |
| US-20060205760-A1 | MOLECULES AND METHODS FOR FLUORESCENCE MICROSCOPY | WISYS TECHNOLOGY FOUNDATION, INC. (US) | 2006-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205760-A1 | MOLECULES AND METHODS FOR FLUORESCENCE MICROSCOPY | NR1H2, NCEH1, NR1H4 | KMT2A 567/4885MEN1 303/4885MAPT 3751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.