Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.84 |
| ▸ | MEN1 | O00255 | 6/20 | 0.84 |
| ▸ | USP2 | O75604 | 3/20 | 0.84 |
| ▸ | MAPT | P10636 | 3/20 | 0.84 |
| ▸ | POLB | P06746 | 3/20 | 0.84 |
| ▸ | ATM | Q13315 | 2/20 | 0.84 |
| ▸ | HTT | P42858 | 2/20 | 0.84 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.84 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.84 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.84 |
| ▸ | RGS12 | O14924 | 1/20 | 0.84 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.84 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.84 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.66 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.66 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.66 |
| ▸ | FLT4 | P35916 | 1/20 | 0.66 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3886877 | 0.95 | KMT2A (0.77) | KMT2AMEN1USP2MAPTPOLB | |
| SCHEMBL9386920 | 0.95 | KMT2A (0.77) | KMT2AMEN1USP2MAPTPOLB | |
| SCHEMBL28087595 | 0.92 | KMT2A (0.83) | KMT2AMEN1USP2MAPTPOLB | |
| SCHEMBL29460431 | 0.91 | KMT2A (1.00) | KMT2AMEN1USP2MAPTPOLB | |
| SCHEMBL372370 | 0.91 | KMT2A (1.00) | KMT2AMEN1USP2MAPTPOLB | |
| SCHEMBL7523337 | 0.91 | KMT2A (0.84) | KMT2AMEN1USP2MAPTPOLB | |
| SCHEMBL1580657 | 0.88 | KMT2A (0.84) | KMT2AMEN1USP2MAPTPOLB | |
| SCHEMBL1505179 | 0.88 | KMT2A (0.88) | KMT2AMEN1USP2MAPTPOLB | |
| SCHEMBL31373066 | 0.88 | MEN1 (0.64) | KMT2AMEN1USP2MAPTPOLB | |
| SCHEMBL8397978 | 0.87 | KMT2A (0.86) | KMT2AMEN1USP2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107501179-B | Water-soluble copper ion fluorescent probe material based on naphthalimide dicarboxylic acid and preparation and application thereof | 兰州交通大学 | 2020-08-07 | — | — | CN | claimed |
| CN-107501179-A | It is a kind of based on the water-soluble copper ion fluorescence probe material of naphthalimide dicarboxylic acids and its preparation and application | 兰州交通大学 | 2017-12-22 | — | — | CN | claimed |
| CN-110305286-B | Waterborne polyurethane based on 1, 8-naphthalimide substituted s-triazine diol derivative and preparation and application thereof | DONGHUA UNIVERSITY (CN) | 2021-08-31 | — | — | CN | disclosed |
| US-10851185-B2 | Bonding tissues and cross-linking proteins with naphthalimide compounds | ALUMEND, LLC (US) | 2020-12-01 | — | — | US | disclosed |
| CN-107501179-B | Water-soluble copper ion fluorescent probe material based on naphthalimide dicarboxylic acid and preparation and application thereof | 兰州交通大学 | 2020-08-07 | — | — | CN | disclosed |
| CN-110305286-A | A kind of aqueous polyurethane and its preparation and application based on 1,8- naphthalimide substitution s-triazine diol, derivatives | 东华大学 | 2019-10-08 | — | — | CN | disclosed |
| US-20190241680-A1 | Bonding tissues and cross-linking proteins with naphthalimide compounds | ALUMEND, LLC (US) | 2019-08-08 | — | — | US | disclosed |
| US-10053521-B2 | Bonding tissues and cross-linking proteins with naphthalimide compounds | ALUMEND, LLC (US) | 2018-08-21 | — | — | US | disclosed |
| US-20180079833-A1 | BONDING TISSUES AND CROSS-LINKING PROTEINS WITH NAPHTHALIMIDE COMPOUNDS | ALUMEND, LLC (US) | 2018-03-22 | — | — | US | disclosed |
| CN-107501179-A | It is a kind of based on the water-soluble copper ion fluorescence probe material of naphthalimide dicarboxylic acids and its preparation and application | 兰州交通大学 | 2017-12-22 | — | — | CN | disclosed |
| US-9822189-B2 | Bonding tissues and cross-linking proteins with naphthalimide compounds | ALUMEND LLC (US) | 2017-11-21 | — | — | US | disclosed |
| US-20130230472-A1 | BONDING TISSUES AND CROSS-LINKING PROTEINS WITH NAPHTHALIMIDE COMPOUNDS | ALUMEND, LLC (US) | 2013-09-05 | — | — | US | disclosed |
| US-20130165970-A1 | BONDING TISSUES AND CROSS-LINKING PROTEINS WTH NAPHTHALIMIDE COMPOUNDS | ALUMEND, LLC (US) | 2013-06-27 | — | — | US | disclosed |
| US-20130045171-A1 | BONDING TISSUES AND CROSS-LINKING PROTEINS WITH NAPHTHALIMIDE COMPOUNDS | ALUMEND, LLC (US) | 2013-02-21 | — | — | US | disclosed |
| US-8242114-B2 | Bonding tissues and cross-linking proteins with naphthalimide compounds | ALUMEND LLC (US) | 2012-08-14 | — | — | US | disclosed |
| EP-2047866-B1 | Bonding tissues and cross-linking proteins with naphthalimide compounds | PHOTOBIOMED CORP (US) | 2011-04-20 | — | — | EP | disclosed |
| US-20090181927-A1 | BONDING TISSUES AND CROSS-LINKING PROTEINS WITH NAPHTHALIMIDE COMPOUNDS | PHOTOBIOMED CORPORATION (US) | 2009-07-16 | — | — | US | disclosed |
| EP-2047866-A1 | Bonding tissues and cross-linking proteins with naphthalimide compounds | PhotoBioMed Corporation (US) | 2009-04-15 | — | — | EP | disclosed |
| US-7514399-B2 | Use in tissue bonding and protein cross-linking and use in tissue and arterial repair, preservation of expanded internal luminal diameters, and local delivery of drugs, skin care materials, sunscreens, and cosmetics | PHOTOBIOMED CORPORATION (US) | 2009-04-07 | — | — | US | disclosed |
| US-20050113288-A1 | Use in tissue bonding and protein cross-linking and use in tissue and arterial repair, preservation of expanded internal luminal diameters, and local delivery of drugs, skin care materials, sunscreens, and cosmetics | PHOTOBIOMED CORPORATION (US) | 2005-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113288-A1 | Use in tissue bonding and protein cross-linking and use in tissue and arterial repair, preservation of expanded internal luminal diameters, and local delivery of drugs, skin care materials, sunscreens, and cosmetics | AAAS, SUN2, TAGLN2 | KMT2A 4168/4885MEN1 1430/4885USP2 845/4885 |
| US-20090181927-A1 | BONDING TISSUES AND CROSS-LINKING PROTEINS WITH NAPHTHALIMIDE COMPOUNDS | SUN2, TAGLN2, DCLRE1A | KMT2A 3756/4885MEN1 1303/4885USP2 1966/4885 |
| US-10053521-B2 | Bonding tissues and cross-linking proteins with naphthalimide compounds | SUN2, BMP2, TAGLN2 | KMT2A 3818/4885MEN1 638/4885USP2 2203/4885 |
| US-20130230472-A1 | BONDING TISSUES AND CROSS-LINKING PROTEINS WITH NAPHTHALIMIDE COMPOUNDS | SUN2, TAGLN2, DCLRE1A | KMT2A 3756/4885MEN1 1303/4885USP2 1966/4885 |
| US-20180079833-A1 | BONDING TISSUES AND CROSS-LINKING PROTEINS WITH NAPHTHALIMIDE COMPOUNDS | SUN2, BMP2, TAGLN2 | KMT2A 3818/4885MEN1 638/4885USP2 2203/4885 |
| US-20130045171-A1 | BONDING TISSUES AND CROSS-LINKING PROTEINS WITH NAPHTHALIMIDE COMPOUNDS | SUN2, TAGLN2, DCLRE1A | KMT2A 3756/4885MEN1 1303/4885USP2 1966/4885 |
| US-10851185-B2 | Bonding tissues and cross-linking proteins with naphthalimide compounds | BMP2, SUN2, TAGLN2 | KMT2A 3736/4885MEN1 602/4885USP2 2263/4885 |
| US-20190241680-A1 | Bonding tissues and cross-linking proteins with naphthalimide compounds | BMP2, SUN2, TAGLN2 | KMT2A 3736/4885MEN1 602/4885USP2 2263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.