SCHEMBL3887159

SCHEMBL3887159

O=C(O)CCc1ccc(OCC2CCCC2)c(-c2ccc3cc(NCCO)ccc3c2)c1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 7/20 0.44
THRA P10827 1/20 0.43
THRB P10828 1/20 0.43
C5AR1 P21730 1/20 0.41
S1PR1 P21453 1/20 0.40
ABL1 P00519 1/20 0.39
PPARD Q03181 2/20 0.38
PPARA Q07869 1/20 0.38
SRC P12931 4/20 0.37
FFAR1 O14842 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3681291 0.88 C5AR1 (0.46) FFAR4THRATHRBC5AR1S1PR1
SCHEMBL3883780 0.88 FFAR4 (0.46) FFAR4THRATHRBC5AR1S1PR1
SCHEMBL3883616 0.86 C5AR1 (0.48) FFAR4THRATHRBC5AR1S1PR1
SCHEMBL3882832 0.86 C5AR1 (0.46) FFAR4THRATHRBC5AR1S1PR1
SCHEMBL3888525 0.86 C5AR1 (0.45) FFAR4THRATHRBC5AR1S1PR1
SCHEMBL3882142 0.85 C5AR1 (0.44) FFAR4THRATHRBC5AR1S1PR1
SCHEMBL3682868 0.85 FFAR4 (0.43) FFAR4THRATHRBC5AR1S1PR1
SCHEMBL3675617 0.85 FFAR4 (0.43) FFAR4THRATHRBC5AR1S1PR1
SCHEMBL3883274 0.85 FFAR4 (0.55) FFAR4THRATHRBC5AR1S1PR1
SCHEMBL3881805 0.84 THRA (0.47) FFAR4THRATHRBC5AR1S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1477472-B1 SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF ASAHI KASEI PHARMA CORP (JP) 2009-01-14 EP claimed
US-6867320-B2 Substituted phenylalkanoic acid derivatives and use thereof ASAHI KASEI PHARMA CORPORATION (JP) 2005-03-15 US claimed
EP-1477472-A1 SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF Asahi Kasei Pharma Corporation (JP) 2004-11-17 EP claimed
US-20040044258-A1 Substituted phenylalkanoic acid derivatives and use thereof ASAHI KASEI PHARMA CORPORATION (JP) 2004-03-04 US claimed
EP-1477472-B1 SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF ASAHI KASEI PHARMA CORP (JP) 2009-01-14 EP disclosed
US-6867320-B2 Substituted phenylalkanoic acid derivatives and use thereof ASAHI KASEI PHARMA CORPORATION (JP) 2005-03-15 US disclosed
EP-1477472-A1 SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF Asahi Kasei Pharma Corporation (JP) 2004-11-17 EP disclosed
US-20040044258-A1 Substituted phenylalkanoic acid derivatives and use thereof ASAHI KASEI PHARMA CORPORATION (JP) 2004-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040044258-A1 Substituted phenylalkanoic acid derivatives and use thereof PTGER1, CYSLTR1, PTGS1 FFAR4 115/4885THRA 1720/4885THRB 3187/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.