Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | EP300 | Q09472 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3887393 | 1.00 | KMT2A (0.60) | KMT2AL3MBTL1POLBMEN1ALDH1A1 | |
| SCHEMBL3886224 | 0.78 | KMT2A (0.54) | KMT2AL3MBTL1POLBMEN1ALDH1A1 | |
| SCHEMBL3886216 | 0.78 | KMT2A (0.54) | KMT2AL3MBTL1POLBMEN1ALDH1A1 | |
| SCHEMBL11045187 | 0.78 | KMT2A (0.81) | KMT2AL3MBTL1POLBMEN1ALDH1A1 | |
| SCHEMBL420585 | 0.78 | KMT2A (0.72) | KMT2AL3MBTL1POLBMEN1ALDH1A1 | |
| SCHEMBL6654185 | 0.77 | PTGS2 (0.68) | KMT2AL3MBTL1POLBMEN1ALDH1A1 | |
| SCHEMBL6654187 | 0.77 | PTGS2 (0.68) | KMT2AL3MBTL1POLBMEN1ALDH1A1 | |
| SCHEMBL3887258 | 0.75 | KMT2A (0.53) | KMT2AL3MBTL1POLBMEN1ALDH1A1 | |
| SCHEMBL3887256 | 0.75 | KMT2A (0.53) | KMT2AL3MBTL1POLBMEN1ALDH1A1 | |
| SCHEMBL4749100 | 0.75 | KMT2A (0.55) | KMT2AL3MBTL1POLBMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534273-B2 | Cationic pyrazolone dyes, method for production thereof and coloring agents for keratin fibers containing said compounds | WELLA AG (DE) | 2009-05-19 | — | — | US | disclosed |
| US-20080263787-A1 | Cationic Pyrazolone Dyes, Method for Production Thereof and Coloring Agents for Keratin Fibers Containing Said Compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2008-10-30 | — | — | US | disclosed |
| EP-1771517-A1 | CATIONIC PYRAZOLONE DYES METHOD FOR PRODUCTION THEREOF AND COLOURING AGENTS FOR KERATIN FIBRES CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006012934-A1 | CATIONIC PYRAZOLONE DYES METHOD FOR PRODUCTION THEREOF AND COLOURING AGENTS FOR KERATIN FIBRES CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2006-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080263787-A1 | Cationic Pyrazolone Dyes, Method for Production Thereof and Coloring Agents for Keratin Fibers Containing Said Compounds | KRT18, KLK5, IK | KMT2A 3682/4885L3MBTL1 4866/4885POLB 2970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.