Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 11/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.39 |
| ▸ | ACP1 | P24666 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11996413 | 1.00 | CA9 (0.46) | CA9MAPTALDH1A1MEN1POLB | |
| SCHEMBL11996394 | 1.00 | CA9 (0.46) | CA9MAPTALDH1A1MEN1POLB | |
| SCHEMBL3891185 | 0.94 | MAPT (0.41) | CA9MAPTALDH1A1MEN1POLB | |
| SCHEMBL3890600 | 0.89 | PTGES (0.45) | CA9MAPTALDH1A1MEN1POLB | |
| SCHEMBL3897116 | 0.89 | PTGES (0.45) | CA9MAPTALDH1A1MEN1POLB | |
| SCHEMBL3897108 | 0.89 | PTGES (0.45) | CA9MAPTALDH1A1MEN1POLB | |
| SCHEMBL3890606 | 0.89 | PTGES (0.45) | CA9MAPTALDH1A1MEN1POLB | |
| SCHEMBL11996460 | 0.85 | PTGES (0.43) | CA9MAPTALDH1A1MEN1POLB | |
| SCHEMBL11996461 | 0.85 | PTGES (0.43) | CA9MAPTALDH1A1MEN1POLB | |
| SCHEMBL3896015 | 0.85 | PTGES (0.43) | CA9MAPTALDH1A1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137133-A2 | 5-SUBSTITUTED-2-IMINO-THIAZOLIDINONE COMPOUNDS AND THEIR USE AS INHIBITORS OF BACTERIAL INFECTION | UNIVERSITY OF WASHINGTON (US) | 2009-11-12 | — | — | WO | disclosed |